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NIDA Notes Articles: Stress

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Stress-Induced Enzyme Compounds Methamphetamine Neurotoxicity

January 2014
Ketoprofen, an anti-inflammatory agent commonly prescribed to treat arthritis, reduces neuronal damage in rats that have been exposed to chronic stress and methamphetamine. If this finding of a recent NIDA-supported study extrapolates to humans, anti-inflammatory medications may gain a place in the treatment of methamphetamine addiction.

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Stressful Experiences Affect Likelihood of Remission of Drug Dependence, Continued Drug Use, and Relapse

February 2018
Stressful life events are associated with reductions in a person’s chances of becoming or remaining abstinent from drugs for at least 3 years.

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