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NIDA Notes Articles: Relapse and Recovery

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New Therapy Reduces Drug Abuse Among Patients With Severe Mental Illness

June 2008
Describes a new intervention that enhances recovery prospects for substance abusers whose mental illness complicates the path toward recovery.

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New Tools and Strategies to Bolster Behavioral Therapy

October 2010
Reports on research investigating whether certain medications might strengthen patients' understanding and memory retention.

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New Vaccines Are Being Developed Against Addiction and Relapse

December 2008
Highlights NIDA-funded research to develop vaccines against addiction to drugs such as cocaine, nicotine, phencyclidine (PCP), and methamphetamine.

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Outcomes of Computerized CBT Rival Those of Clinician-Delivered CBT

June 2018
A clinical trial found that patients who self-administered cognitive behavioral therapy (CBT) using computerized training modules reduced their drug use as much as patients who received clinician-delivered CBT, and they maintained this advantage through a 6-month follow-up.

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Physical Activity Reduces Return to Cocaine Seeking in Animal Tests

April 2012
Two independent animal studies suggest that aerobic exercise might help cocaine abusers establish and maintain abstinence.

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Program Enhances Physician Knowledge on Substance Abuse

December 2010
Reports on an evaluation of the Chief Resident Immersion Training (CRIT) program to assess its effectiveness in improving knowledge, confidence, and preparedness to diagnose, manage, and teach about substance abuse.

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Recovery Checkup System Helps Substance Abusers Who Have Mental Disorders

December 2009
Reports on a posttreatment intervention to support recovery that may be especially beneficial for substance abusers with co-occurring mental disorders.

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Recovery May Be Harder for Adolescents, Animal Study Suggests

December 2009
Reports animal study findings that suggest adolescents' heightened sensitivity to drug reward puts them at enhanced risk of addiction and may also increase their challenges in recovery.

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Report Discusses Co-Occurrence of Drug Abuse and Other Mental Disorders

December 2009
Describes an updated report on the co-occurrence, or comorbidity, of substance use disorders and other psychiatric disorders such as ADHD, schizophrenia, and depression.

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Serotonin System May Have Potential as a Target for Cocaine Medications

April 2007
Describes investigations to advance the development of potential drug abuse relapse prevention agents by targeting specific receptors of the neurochemical serotonin.

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