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NIDA Notes Articles: Medication Development

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Endorphin Derivative Inhibits Reward From Morphine and Nicotine in Rats

October 2007
Describes research investigating a naturally occurring brain chemical that shows early promise as a treatment for addiction in animal studies.

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Vaccine May Reduce Fetal Exposure to Nicotine

April 2007
Describes research on a vaccine developed to facilitate smoking cessation by blocking nicotine penetration into the brain.

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Naltrexone-Nicotine Patch Combination Shows Promise

April 2007
Reports findings from a clinical trial investigating the effectiveness of naltrexone as a supplement to nicotine replacement therapy for smoking cessation.

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How Drug Abuse Affects the Brain and Alters Behavior Are Key Questions Driving Division's Work

February 2007
Discusses the work of NIDA’s Division of Basic Neuroscience and Behavioral Research, the Institute’s locus for studies into the fundamental brain mechanisms underlying drug abuse and addiction.

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