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NIDA Notes Articles: Medication Development

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Quinine as a Tracer for Medication Adherence

September 2016
Patients who don’t take their medications as prescribed often put themselves at risk for problems including misdiagnoses, complications, and death. A study suggests that adding low doses of quinine to patients’ medications could provide an inexpensive, reliable, and safe method of monitoring whether patients are taking their medications as directed.

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Stress-Induced Enzyme Compounds Methamphetamine Neurotoxicity

January 2014
Ketoprofen, an anti-inflammatory agent commonly prescribed to treat arthritis, reduces neuronal damage in rats that have been exposed to chronic stress and methamphetamine. If this finding of a recent NIDA-supported study extrapolates to humans, anti-inflammatory medications may gain a place in the treatment of methamphetamine addiction.

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Testing a Prospective Medication To Help People Avoid Relapse

March 2016
This NIDA Notes animation depicts a basic experiment that researchers use to test whether a prospective new medication can prevent relapse to drug addiction.

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