En español

NIDA Notes Articles: Medication Development

NIDA Notes Category Graphic

Gabapentin Tested To Treat Marijuana Dependence

April 2013

Marijuana-dependent outpatients who were treated with the medication gabapentin in a pilot clinical trial reduced their cannabis use more and reported fewer symptoms of drug withdrawal than patients who received a placebo.

NIDA Notes Category Graphic

Endorphin Derivative Inhibits Reward From Morphine and Nicotine in Rats

October 2007

Describes research investigating a naturally occurring brain chemical that shows early promise as a treatment for addiction in animal studies.

NIDA Notes Category Graphic

Dual Regimen Aims To Shorten Medication-Assisted Therapy

May 2016

Treatment that combines use of Bp/Nx and memantine may enable young adults addicted to opioids establish lasting abstinence after a relatively brief course of medication-assisted therapy, a pilot trial suggests.

NIDA Notes Category Graphic

Dr. Thomas Kosten Q & A: Vaccines To Treat Addiction

June 2015

In this article and accompanying podcast, Dr. Thomas Kosten discusses the idea and current status of antidrug vaccines to treat substance use and addiction.

NIDA Notes Category Graphic

Dr. Phil Skolnick Now Leads NIDA's Medications Development Efforts

April 2010
Announces the appointment of Dr. Phil Skolnick as NIDA’s director of the Division of Pharmacotherapies and Medical Consequences of Drug Abuse.

NIDA Notes Category Graphic

Dr. Kevin M. Gray Q & A: A Potential Medication for Marijuana Dependence

October 2014

Dr. Kevin M. Gray discusses why it’s the perfect time for discovering new evidence-based treatments for marijuana dependence. In an accompanying podcast, he discusses a clinical trial that examines NAC’s potential as a treatment for marijuana dependence among adults.

NIDA Notes Category Graphic

Combined Treatments Improve Dual Abstinence

October 2009

Reports on a study investigating the effectiveness of a combined therapy of disulfiram and naltrexone for people who abuse cocaine and alcohol.

NIDA Notes Category Graphic

Cocaine Vaccine Helps Some Reduce Drug Abuse

December 2010

Reports on the results of a clinical trial that tested the effectiveness of a cocaine vaccine designed as a therapy for cocaine abuse and plans underway for a new study of 300 patients to confirm these results.

NIDA Notes Category Graphic

Buprenorphine During Pregnancy Reduces Neonate Distress

July 2012

Sublingual buprenorphine is a safe and effective alternative to methadone for treating opioid dependence during pregnancy, finds the Maternal Opioid Treatment: Human Experimental Research (MOTHER) study, a NIDA-supported clinical trial. Women who received either medication had similar pregnancy and birth outcomes, but infants born to women who received buprenorphine had milder symptoms of neonatal opioid withdrawal.

NIDA Notes Category Graphic

Basic Science Discoveries Yield Novel Approaches to Analgesia

September 2008

Describes research to develop new compounds that match or exceed the pain relief provided by opioids while avoiding their shortcomings.


NIDA Notes


Drug Topics

Drugs of Abuse

Population Groups

Related Topics