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NIDA Notes Articles: Medical Consequences

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Anabolic-Androgenic Steroids May Damage the Heart and Arteries

November 2017
Use of anabolic-androgenic steroids (AAS) is associated with compromised heart pumping and atherosclerotic plaque. Clinicians should inquire about AAS use when young or middle-aged men present with left ventricular dysfunction or coronary artery disease.

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Animal Studies Elaborate Toluene's Effects

June 2008
Reports on evidence that toluene abuse can harm the nervous system and body, although scientists know relatively little about its specific actions.

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Annual Event Teaches Students Brain Science

November 2009
Highlights activities held during Brain Awareness Week for students in Maryland, Virginia, and Washington, DC, to learn about brain anatomy and function.

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Behavioral Problems Related to Maternal Smoking During Pregnancy Manifest Early in Childhood

June 2008
Describes research providing evidence that maternal smoking during pregnancy contributes to behavioral conduct disorders among toddlers, school-age children, and teens.

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Crack Cocaine Promotes Progression of HIV Infection to AIDS

October 2010
Reports on two studies showing a high prevalence of HIV infection and more rapid progression to disability and death among drug abusers.

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Drugs Contribute to High Rates of Sexually Transmitted Diseases Among Juvenile Offenders

July 2011
Describe a study of newly arrested youths where researchers found correlations between the youths' prevalence of these sexually transmitted diseases and their cocaine and marijuana use.

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Extended Cocaine Exposure Impairs Cognitive Function in Rats

November 2009
Reports an animal study presenting evidence that cocaine causes cognitive deficits that can persist well into abstinence.

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Gene Variants Reduce Opioid Risks

June 2014
Two recent studies suggest that genotyping may enable clinicians to base therapies on individual patients’ potential responsiveness to opioid drugs’ therapeutic effects and vulnerability to their harmful effects.

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HIV Infection Accelerates Hepatitis C–Related Liver Fibrosis

January 2014
Study patients with HIV­­–hepatitis C coinfection progressed to successive degrees of severity of liver fibrosis 9 years sooner than those infected with HCV alone. Further findings from the study suggest that suppressing HIV with antiretroviral medications may slow HCV-related liver fibrosis.

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Injection Drug Users Acquire Hepatitis C Infection Later in Developed Countries

April 2010
Reports trends in onset of injection drug use to infection with hepatitis C virus in developed countries and notes the influence of prevention efforts.

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