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Basic Science

How Cocaine Cues Get Planted in the Brain

An epigenetic mechanism underlies the powerful cocaine–environment associations that promote relapse.

Basic Science

A Gene Links Impulsivity and Drug Use Vulnerability

Understanding the relationships between impulsivity and drug use vulnerability may help identify new ways of treating or preventing substance use disorders.

Basic Science

Animal Study Suggests Marijuana May Affect Future Offspring’s Susceptibility to Heroin

Can marijuana use put offspring at heightened risk for opiate addiction, even if the use stops before the offspring are conceived? Results from a recent NIDA-funded study are consistent with other studies suggesting that a parent’s history of drug use, even preconception, may affect a child’s brain function and behavior.

Basic Science

A Genetic Nexus of Obesity and Smoking

Research shows that some gene variants that influence body mass index also shape smoking behaviors.

Basic Science

Gene Variants Reduce Opioid Risks

Two recent studies suggest that genotyping may enable clinicians to base therapies on individual patients’ potential responsiveness to opioid drugs’ therapeutic effects and vulnerability to their harmful effects.

NIDA @ Work

Dr. Joni Rutter Q&A: How Basic Science Is Tackling Addiction

One of NIDA’s goals is to try to understand the individual differences that contribute to whether or not someone who takes a drug will become addicted to it. Dr. Rutter’s research focuses on three types of differences: Environmental, developmental, and genetic and epigenetic.

NIDA Notes

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