An experimental compound with a dual action at two opioid receptors may provide powerful pain relief without many of opioids' harmful side effects.
Mindfulness-Oriented Recovery Enhancement (MORE) reduces opioid misuse among chronic pain patients. MORE shifts patients' attention away from drug cues and toward cues for natural rewards.
Among patients with chronic pain, those who reported less ability to tolerate physical or emotional distress were more likely to misuse opioid analgesics.
One out of every 143 U.S. patients who received a prescription for an opioid painkiller in 2008 obtained prescriptions from multiple physicians in a pattern that suggests misuse or abuse of the drugs.