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Your search for Treatment Research returned 37 results. Search again.

Treatment

Mindful Awareness in Body-Oriented Therapy Proves Useful in Women Treated for Substance Use Disorder

Mindful Awareness in Body-Oriented Therapy (MABT) improved emotion regulation, reduced craving, and promoted abstinence in women with a history of trauma and emotional problems receiving outpatient treatment for substance use disorder.

Basic Science

Machine Learning Applied to Brain Imaging Data Predicts Response to Cocaine Use Disorder Treatment

This study demonstrated that functional connectivity among a large number of brain regions predicts patients’ chances of achieving abstinence in treatment for cocaine use disorder.

Basic Science

Rats Prefer Social Interaction to Heroin or Methamphetamine

This study showed that rats will forgo heroin and methamphetamine in favor of spending time with another rat. It also highlights the importance of incorporating voluntary choice between drugs and social rewards in drug addiction research.

Treatment

Methadone Maintenance Treatment During Incarceration Has Long-Term Benefits

Prisoners who received methadone maintenance treatment (MMT) during incarceration were more likely than prisoners who did not receive MMT to engage in the treatment after being released.

Treatment

Interim Buprenorphine Alleviates Psychiatric Symptoms in Waitlisted OUD Patients

Interim treatment with buprenorphine significantly improved the psychiatric symptoms of people awaiting comprehensive treatment for opioid use disorder (OUD). Buprenorphine treatment, even without concurrent psychosocial counseling, may help patients with no, or delayed, access to comprehensive OUD treatment.

Treatment

A Promising Alternative to Opioid Pain Medications

An experimental compound with a dual action at two opioid receptors may provide powerful pain relief without many of opioids' harmful side effects.

Treatment

Prescription Opioid Misuse Treatment Leverages Mindfulness To Amplify Natural Rewards

Mindfulness-Oriented Recovery Enhancement (MORE) reduces opioid misuse among chronic pain patients. MORE shifts patients' attention away from drug cues and toward cues for natural rewards.

Treatment

Switching to Reduced-Nicotine Cigarettes May Aid in Quitting Smoking

Smokers who switch to cigarettes with very low nicotine content may experience mild and transient increases in some withdrawal symptoms. Cigarettes with reduced nicotine will be easier to quit than the cigarettes marketed at present.

Treatment

Outcomes of Computerized CBT Rival Those of Clinician-Delivered CBT

A clinical trial found that patients who self-administered cognitive behavioral therapy (CBT) using computerized training modules reduced their drug use as much as patients who received clinician-delivered CBT, and they maintained this advantage through a 6-month follow-up.

Treatment

In Animals, Opioid Combination Shows Promise for Safer Pain Relief

In rats, the combination treatment of oxycodone/nalfurafine had lower levels of abuse liability and produced less respiratory depression than oxycodone alone.

Treatment

Novel Compound Alleviates Hard-to-Treat Pain in Mice

A novel compound called GAT211 alleviates inflammatory and neuropathic pain in mice without producing tolerance or signs of abuse liability.

Treatment

Cigarette Smoking Increases the Likelihood of Drug Use Relapse

Research suggests that helping patients quit and remain abstinent from smoking may improve their chances for sustained recovery from use of other drugs.

Narrative of Discovery

Narrative of Discovery: The Quest for a Medication To Treat Methamphetamine Addiction, Part 3

Dr. Linda Dwoskin feels just one small step away from success in her effort to develop the first ever medication to treat methamphetamine addiction.

Treatment

Fear of Distress Signals Risk for Opioid Misuse in Chronic Pain Patients

Among patients with chronic pain, those who reported less ability to tolerate physical or emotional distress were more likely to misuse opioid analgesics.

Narrative of Discovery

Narrative of Discovery: Can Magnets Treat Cocaine Addiction? Part 3

In the final installment of this series, Dr. Diana Martinez navigates the process for receiving NIH funding to test the efficacy of using transcranial magnetic stimulation as treatment for cocaine addiction.

Treatment

Buprenorphine Benefits Waitlisted Seekers of Opioid Treatment

In two pilot clinical trials, buprenorphine helped participants reduce their illicit opioid use and injection drug use while awaiting admission to a methadone or buprenorphine treatment program. Researchers minimized the risks for improper use or diversion of the study medication by giving it to trial participants in a computerized, tamper-proof device that dispenses one dose each day.

Treatment

Nonmedical Treatment for Cocaine Addiction Shows Promise in Pilot Trial

Patients who received transcranial magnetic stimulation (TMS) were more likely to abstain from cocaine than patients who received medications for symptoms associated with abstinence. Researchers concluded that TMS appears to be safe and its efficacy as a treatment for cocaine addiction deserves to be evaluated in a larger clinical trial.

Treatment

Messages Shore Up Support for Making Life-Saving Anti-Overdose Medication Widely Available

Public health messages can increase public approval for making naloxone legally available to friends and relatives of opioid users to administer if an overdose occurs.

Treatment

Quinine as a Tracer for Medication Adherence

Patients who don’t take their medications as prescribed often put themselves at risk for problems including misdiagnoses, complications, and death. A study suggests that adding low doses of quinine to patients’ medications could provide an inexpensive, reliable, and safe method of monitoring whether patients are taking their medications as directed.

Treatment

Slow-Release Amphetamine Medication Benefits Patients With Comorbid Cocaine Addiction and ADHD

Treatment with an extended-release stimulant medication plus cognitive behavioral therapy was associated with reductions in cocaine use and in attention-deficit/hyperactivity disorder symptoms in patients with both disorders.

Narrative of Discovery

Narrative of Discovery: Can Magnets Treat Cocaine Addiction? Part 2

During investigations into using transcranial brain stimulation (TMS) to treat cocaine abuse, two projects take diverging paths. One researcher moves to the next stage, while another is forced to cut his trial short. 

Treatment

Dual Regimen Aims To Shorten Medication-Assisted Therapy

Treatment that combines use of Bp/Nx and memantine may enable young adults addicted to opioids establish lasting abstinence after a relatively brief course of medication-assisted therapy, a pilot trial suggests.

Narrative of Discovery

Narrative of Discovery: In Search of a Medication To Treat Methamphetamine Addiction, Part 2

When lobeline turned out not to be the answer, it became a starting point. Dr. Linda Dwoskin and her team set out to transform the molecule into something more effective and with fewer side effects.

Treatment

Testing a Prospective Medication To Help People Avoid Relapse

This NIDA Notes animation depicts a basic experiment that researchers use to test whether a prospective new medication can prevent relapse to drug addiction.

Treatment

ED-Initiated Buprenorphine Outperforms Referral or SBIRT for ED Patients With Opioid Addiction

Emergency department visits present prime opportunities to identify people with opioid addiction and provide them with onsite initiation of treatment with buprenorphine/naloxone.

Treatment

Long-Term Follow-Up of Medication-Assisted Treatment for Addiction to Pain Relievers Yields “Cause for Optimism”

In the first long-term follow-up of patients treated with buprenorphine/naloxone for addiction to opioid pain relievers, half reported that they were abstinent from the drugs 18 months after starting the therapy.

Treatment

Digital Addiction Therapies Affirm Promise in Replication and Large Trial

Two computerized programs improved outcomes when they were used to supplement or partially replace in-person behavioral therapy for drug addiction in recent NIDA-sponsored trials.

Narrative of Discovery

Narrative of Discovery: Can Magnets Treat Cocaine Addiction?

Two researchers share their reasons for researching transcranial magnetic stimulation (TMS) for treating cocaine addiction, and describe challenges to moving forward this potentially promising therapy.

Treatment

A Rapid Teen Substance Use Screening Tool for Clinicians

Answers to three simple questions can help a busy health care provider flag a teen’s problematic use of alcohol, tobacco, or marijuana.

Treatment

Electronic Questionnaire Quickly Rates Teens’ Substance Use

With a few simple questions, a new screening tool detects whether a teen is likely to have a mild-to-moderate or a severe substance use disorder.

Treatment

Study Ranks Recovery Assets in Cocaine Addiction

A can-do attitude, ability to cope with potential triggers for drug use, readiness to change, and participation in self-help programs are major assets for people trying to recover from cocaine addiction.

Treatment

Text Messaging Aftercare Intervention Cuts Youths’ Risk for Relapse

An interactive mobile texting aftercare program has shown promise as a means to help teens and young adults engage with post-treatment recovery activities and avoid relapse. The program reduced young people’s odds of relapsing by half compared with standard aftercare.

Treatment

Dr. Thomas Kosten Q & A: Vaccines To Treat Addiction

In this article and accompanying podcast, Dr. Thomas Kosten discusses the idea and current status of antidrug vaccines to treat substance use and addiction.

Treatment

Study Points to Individualized Therapy for Opioid Addiction

Trial participants who were addicted to opioid painkillers and did not inject drugs stayed in treatment longer and achieved better outcomes than those who were addicted to heroin or injected drugs.

Treatment

Patients Addicted to Opioid Painkillers Achieve Good Results With Outpatient Detoxification

A significant portion of individuals who are addicted to opioid painkillers may initiate and maintain abstinence with a brief but intensive outpatient detoxification treatment followed by opioid antagonist therapy using naltrexone.

Narrative of Discovery

Narrative of Discovery: In Search of a Medication To Treat Methamphetamine Addiction

This is the first in a series of NIDA Notes articles that will follow a team of researchers seeking a medication for methamphetamine addiction. This installment describes the early promise of the compound lobeline and the new directions the team discovered in studying it.

NIDA Notes

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