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Basic Science

Part 2: Immunotherapies—A New Tool To Treat Methamphetamine Addiction?

Researchers move their monoclonal antibody (mAb) into clinical trials to see if it can be an effective treatment for methamphetamine use.

Basic Science

Part 1: Immunotherapies—A New Tool To Treat Methamphetamine Addiction?

Researchers have created a monoclonal antibody (mAb) that is intended to interact with methamphetamine and decrease its ability to enter the brain.

Basic Science

Nerve-Cell Growth During Abstinence From Methamphetamine May Promote Reinstatement of Drug Use in Rats

Neurogenesis that occurs during abstinence from methamphetamine in a brain region related to memory and learning may promote relapse-like behavior.

Basic Science

Rats Prefer Social Interaction to Heroin or Methamphetamine

This study showed that rats will forgo heroin and methamphetamine in favor of spending time with another rat. It also highlights the importance of incorporating voluntary choice between drugs and social rewards in drug addiction research.

Narrative of Discovery

Narrative of Discovery: The Quest for a Medication To Treat Methamphetamine Addiction, Part 4

Dr. Linda Dwoskin wins a NIDA grant to continue her team's work to find a medication to treat methamphetamine addiction—but there's a string attached.

Basic Science

La metanfetamina altera las estructuras cerebrales y perjudica la flexibilidad mental

Los investigadores patrocinados por el NIDA mostraron que, en los monos, la metanfetamina altera las estructuras cerebrales involucradas en la toma de decisiones y afecta negativamente la capacidad de eliminar los comportamientos habituales que se han vuelto inútiles o contraproducentes.

Narrative of Discovery

Narrative of Discovery: The Quest for a Medication To Treat Methamphetamine Addiction, Part 3

Dr. Linda Dwoskin feels just one small step away from success in her effort to develop the first ever medication to treat methamphetamine addiction.

Narrative of Discovery

Narrative of Discovery: In Search of a Medication To Treat Methamphetamine Addiction, Part 2

When lobeline turned out not to be the answer, it became a starting point. Dr. Linda Dwoskin and her team set out to transform the molecule into something more effective and with fewer side effects.

NIDA Notes

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