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Genes linked to hepatitis C viral clearance could lead to personalized treatments

Science Spotlight

March 27, 2013

NIDA AIDS Research Program

A NIH-funded study, published February 19 in the Annals of Internal Medicine, shows that possessing either of two specific gene variants make it more likely that a patient’s own immune system can successfully fight off hepatitis C infection (i.e., without the need for medications). Furthermore, if a person possesses both, the chances of clearing the virus are even greater. These results may predict which patients will respond more favorably to hepatitis C treatment.

For a copy of the study abstract, go to http://annals.org/article.aspx?articleid=1650774#Abstract. For details on NIDA’s AIDS Research Program, go to www.drugabuse.gov/about-nida/organization/offices/office-nida-director-od/aids-research-program-arp. For a copy of a press release from Johns Hopkins Medicine, go to http://www.hopkinsmedicine.org/news/media/releases/studies_advance_knowledge_of_hiv_impact_on_hepatitis_c_infection_and_genes_that_may_thwart_hepatitis_c_infection.

For more information, contact the NIDA press office at media@nida.nih.gov or 301-443-6245.

NIDA Press Office

About the National Institute on Drug Abuse (NIDA): The National Institute on Drug Abuse (NIDA) is a component of the National Institutes of Health, U.S. Department of Health and Human Services. NIDA supports most of the world’s research on the health aspects of drug use and addiction. The Institute carries out a large variety of programs to inform policy, improve practice, and advance addiction science. Fact sheets on the health effects of drugs and information on NIDA research and other activities can be found at www.drugabuse.gov, which is now compatible with your smartphone, iPad or tablet. To order publications in English or Spanish, call NIDA’s DrugPubs research dissemination center at 1-877-NIDA-NIH or 240-645-0228 (TDD) or email requests to drugpubs@nida.nih.gov. Online ordering is available at drugpubs.drugabuse.gov. NIDA’s media guide can be found at www.drugabuse.gov/publications/media-guide/dear-journalist, and its easy-to-read website can be found at www.easyread.drugabuse.gov. You can follow NIDA on Twitter and Facebook.

About the National Institutes of Health (NIH): NIH, the nation’s medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit www.nih.gov.

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    NIDA. (2013, March 27). Genes linked to hepatitis C viral clearance could lead to personalized treatments. Retrieved from https://www.drugabuse.gov/news-events/news-releases/2013/03/genes-linked-to-hepatitis-c-viral-clearance-could-lead-to-personalized-treatments

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