Nicotine addiction linked to diabetes through a DNA-regulating gene in animal models
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Researchers have discovered a mechanism in rats that links cigarette smoking and the risk of developing type 2 diabetes.
Latest from NIDA
Machine Learning Applied to Brain Imaging Data Predicts Response to Cocaine Use Disorder Treatment
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This study demonstrated that functional connectivity among a large number of brain regions predicts patients’ chances of achieving abstinence in treatment for cocaine use disorder.
NIDA-NIAAA 2019 Mini-Convention: Frontiers in Addiction Research
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The National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA), both part of the National Institutes of Health, will host a one-day mini-convention...
Measuring sleep challenges in opioid use disorder patients
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A new study at NIDA’s Intramural Research Center measured sleep patterns in opioid use disorder patients and found that clinic appointment hours make a difference in sleep quality. They also...
Teen e-cigarette use doubles since 2017
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Data from the 2019 Monitoring the Future Survey of eighth, 10th and 12th graders show alarmingly high rates of e-cigarette use compared to just a year ago, with rates doubling...
Marijuana use at historic highs among college-age adults
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Newly released Monitoring the Future (MTF) survey data on drug use in college-age adults ages 19-22 shows an increase in marijuana use in the past five years, including vaping with...
CDC and FDA Issue Updates on Vaping-Related Health Issues
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The CDC and FDA have posted important information for consumers related to recent deaths and illnesses that could be linked to vaping.
NASEM releases National Agenda on Children’s Behavioral Health
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The National Academies of Sciences, Engineering and Medicine has released a national scientific agenda on Fostering Healthy Mental, Emotional, and Behavioral Development in Children and Youth, recommending a comprehensive approach...
Unraveling the mystery of the glutamate-dopamine connection
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Investigators identify a subpopulation of calbindin neurons with the capability to co-release glutamate and dopamine in the nucleus accumbens shell.
U.S. Surgeon General Warning on Marijuana Use in Adolescence and During Pregnancy
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The U.S. Surgeon General has issued a warning about the potential health risks of marijuana use in adolescence and during pregnancy.
Worms lead scientists to a new anti-opioid system
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A team of NIH-funded scientists used worms to discover a surprising biological system that counteracts the effects of opioids, offering a potential new target for improving the safety of opioid...
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This study showed that rats will forgo heroin and methamphetamine in favor of spending time with another rat. It also highlights the importance of incorporating voluntary choice between drugs and...
New findings could lead to reduced replication of the HIV virus
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In this study, NIDA-funded scientists found that the HIV RNA genome has two previously unknown types of RNA marks.
Teens who misuse medicines get them from multiple sources
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Two NIDA-funded studies have found that adolescents using multiple sources for prescription medications are at high risk for other substance use.
Co-prescribing naloxone in Medicare Part D increases
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A study found that overall national rates for naloxone co-prescription along with any opioid among Medicare Part D patients increased from 1.5 per 1000 patients receiving opioid prescriptions in 2016...
THC Exposure in Adolescence Disrupts Brain Maturation in Animals
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A NIDA-supported study may help explain observed links between adolescent marijuana use and vulnerability to psychiatric disorders.
First time drug use more common in summertime
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Government surveys showed that in 2017, an estimated three million people tried marijuana for the first time, just over a million tried cocaine, close to 800,000 tried LSD, and close...
Parenting programs lead to healthier behaviors
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A study conducted among 517 youth in the rural areas of the southeastern United States demonstrates the effectiveness of a parenting enhancement program in both preventing drug use and obesity...
NIH establishes network to improve opioid addiction treatment in criminal justice settings
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The National Institutes of Health will award 12 grants to form the Justice Community Opioid Innovation Network (JCOIN) to support research on quality addiction treatment for opioid use disorder (OUD)...
Similarities between aggressive and addictive behaviors
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Scientists from NIDA’s Intramural Research Program show that neural mechanisms that control appetitive aggressive behavior are similar to those that control drug-taking and seeking (relapse), suggesting common neurobiological mechanisms of...
Drug Use and Its Consequences Increase Among Middle-Aged and Older Adults
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Studies found: The spread of marijuana use and the opioid epidemic over the past 10 years have affected middle-aged and older Americans. Prescription opioid and benzodiazepine misuse increased older adults’...
Prescription opioid misuse in high school linked to later heroin use
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A NIDA-funded study suggests that misuse of prescription opioid pain relievers in high school could be linked to heroin use later in life.
Medical Marijuana Laws and Opioid Overdose Rates
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A new study underscores the need for additional research on the effect of medical marijuana laws on opioid overdose deaths and cautions against drawing a causal connection between the two.
Female reproductive cycle affects cocaine craving in animal study
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Researchers at NIDA’s Intramural Research Program (IRP) wanted to determine if the incubation of craving would be different in male and female rats and if the effect is stronger after...
Nicotine and Cannabis Have Offsetting Effects on Resting Brain Connectivity
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This research: Adds to research showing that nicotine and cannabis have interactive effects on brain structure and function. Suggests that specialized treatment interventions may be appropriate for people who use...
Study finds increased cannabis use during pregnancy
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Cannabis use more than doubled among pregnant women in the United States during the period 2002-2017.
Cannabis Dependence Is Associated With Changes in Neural Circuitry That May Contribute to Psychopathology
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People with cannabis dependence have changes in neural circuitry in brain regions related to reward processing, habit formation, and psychopathology. These changes in neural circuitry may provide a useful marker...
Project to deter opioid tampering wins 2019 NIDA Addiction Science Award
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A 14-year-old’s innovative approach to prevent tampering and misuse of opioid pills won a first place Addiction Science Award at the 2019 Intel International Science and Engineering Fair (ISEF)—the world’s...
National Institute on Drug Abuse Intramural Research Program Holds Opioid Symposium
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The National Institute on Drug Abuse (NIDA) Intramural Research Program will hold a one-day symposium to summarize the most recent advances in opioid research.
Brief drug use disrupts learning mechanisms in the brain
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In a new animal study, scientists at NIDA’s Intramural Research Program have demonstrated that cocaine use profoundly disrupts these teaching signals.