Disrupting Cocaine Memories Prevents Return to Cocaine Use in Rats
|
Preventing cocaine memories from re-strengthening in an unstable period following retrieval attenuates cocaine seeking.
Latest from NIDA
To end HIV epidemic, we must address health disparities
|
Expert report cites unequal progress in Southern U.S. and among marginalized groups
Human Opioid Exposure Can Be Measured Using Wastewater
|
Using robotic technology, local levels of opioid metabolites can be measured in wastewater from individual manholes
Co-located HIV Services Can Help Women Who Inject Drugs Access PrEP, Study Shows
|
Daily, PrEP (pre-exposure prophylaxis medication), is proven to prevent HIV transmission from injection drug use or sex.
Skewed Opioid Prescribing Patterns in the United States—A Few Providers Prescribe a Large Proportion of Opioids
|
Only 1 percent of the providers who prescribe opioids account for almost half of all opioid doses prescribed and one-quarter of opioid prescriptions written.
Methamphetamine overdose deaths rise sharply nationwide
|
NIH-supported study finds biggest increase among American Indians and Alaska Natives
Combination treatment for methamphetamine use disorder shows promise in NIH study
|
Combination medication may be effective in treating adults with methamphetamine use disorder
People With SUDs Have Increased Risk for COVID-19 and Worse Outcomes
|
People with a substance use disorder (SUD) at any time in their lives are 1.5 times more likely to contract COVID-19 than those without an SUD, and those with a...
Physician-pharmacist collaboration may increase adherence to opioid addiction treatment
|
NIH-supported pilot study found team-based approach may improve buprenorphine care
Substance Use Status Important When Developing HIV Therapies
|
Animal studies suggest that subjects with HIV who suffer from opioid use disorders may have higher viral reservoirs in the central nervous system than non-opioid users.
Decision-Making in Ambiguous Situations Influences OUD Patients’ Relapse Risk
|
Patients in treatment for opioid use disorder (OUD) who were more comfortable making decisions when they did not know the probability of outcome had a higher risk of using opioids...
Study: Surge of teen vaping levels off, but remains high as of early 2020
|
Annual Monitoring the Future (MTF) survey results released.
Unraveling neuroHIV in the Presence of Substance Use Disorders
|
These reviews address how each of these addictive substances and HIV individually or collectively affect the immune system and subsequent clinical and behavioral outcomes
How the Brain Makes Pain Unpleasant
|
A specific collection of neurons in the basolateral amygdala, a brain region crucial for affect, was active when mice experienced pain. Deactivating this collection of neurons resulted in a loss...
Elite Controllers May Hold Key to an HIV Cure
|
"Science" Magazine Breakthrough of the Year Runner Up for 2020
Amy Hauck Newman appointed to lead NIDA’s Intramural Research Program
|
Dr. Newman officially began her new position at the NIDA IRP on November 22, 2020.
HIV and Methamphetamine Use: Double Jeopardy for Transmission of the Novel Coronavirus.
|
The authors suggest that co-occurring methamphetamine use and HIV present a double jeopardy for COVID.
Neighborhood conditions associated with children’s cognitive function
|
NIH-funded research from ABCD Study finds association despite household income.
NIH study tests a comprehensive model intervention to reduce opioid overdose deaths in hard-hit communities
|
COVID-19 brings challenges, learning opportunities
NIH-funded study links adolescent brain differences to increased waist circumference
|
Finding from ABCD Study elucidates neural mechanisms that may underlie early weight gain
Narrative of Discovery: The Quest for a Medication to Treat Methamphetamine Addiction, Part 5
|
In the summer of 2019, Dr. Linda Dwoskin and her research team felt they were in a promising place in their decades-long search for a treatment for the 700,000 Americans...
|
Increases are among the largest in history of national study
Gaps in Substance Use Treatment Services for HIV Patients Around the Globe
|
Substance use is common among people living with HIV and is associated with less successful HIV treatment outcomes. Integrating substance use services into HIV care is a promising strategy to...
Substance use disorders linked to COVID-19 susceptibility
|
NIH research finds higher risk and worse outcomes for those with addiction
Cocaine Triggers Endocannabinoid Release Through a Novel Mechanism
|
Cocaine can trigger release of the endocannabinoid 2-arachidonoylglycerol (2-AG) in the ventral tegmental area of the midbrain in mice, and this may play a role in cocaine use disorder.
Prenatal Cannabis Exposure Alters Brain Reward Circuitry in Male Rats
|
Prenatal cannabis exposure (PCE) increased sensitivity to THC in male rats, but not female rats, during pre-adolescence. PCE increased dopamine release in response to THC and altered the properties of...
Two Different Brain Regions Are Linked With Nicotine Addiction Severity and Nicotine Withdrawal
|
Activity in the striatum of people who smoke changed less in response to positive feedback/reward than in nonsmokers; this effect was more pronounced with greater addiction severity. Activity of the...
Treating Substance Use Disorders Can Reduce HIV Burden in U.S. Cities
|
Concerted efforts and substantial investments in HIV prevention and care in the United States have resulted in considerable reduction in new diagnoses and death since the mid-1990s. To identify best...
Parents’ Marijuana Use May Increase Children’s Risk of Marijuana Use and Favorable Views of Marijuana
|
This study found that children’s risk of marijuana and alcohol use and attitudes toward marijuana were influenced by their parents’ marijuana use pattern over time.
Clues to Regulating HIV-1 Viral Gene Expression
|
People with substance use disorders (SUD) can be at high risk for contracting this virus, either through injection drug use, or risky behaviors prompted by impaired judgment.