Disparities in opioid overdose deaths continue to worsen for Black people, study suggests
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NIH-supported study underscores the need for racially inclusive approach to address the opioid crisis in hard-hit areas
Latest from NIDA
Marijuana use at historic high among college-aged adults in 2020
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Annual NIH-supported study reports changing substance use trends among college students and college-aged adults
NIH HEAL Initiative: Research Meets the Moment to Address the Opioid Public Health Crisis
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Directors highlight research results from NIH-funded science and community partnerships
Chronic Cocaine Use Changes Brain Structure and Cognitive Function in Rhesus Monkeys
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Specific cocaine-induced decreases in gray matter density were associated with reduced performance on tests of memory and cognition.
NIH-funded study finds overall rate of drug use among 10-14 year-olds remained stable during the 2020 COVID-19 pandemic
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Adolescents experiencing stress, mental health issues, and hardship most likely to use substances
Reduced Activity in One Brain Region Links Childhood Adversity to Aggression/Delinquency and Substance Use in Adolescence
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People who experienced more childhood adversity had higher rates of substance use in late adolescence.
More than 1.5 million children lost a primary or secondary caregiver due to the COVID-19 pandemic
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Addressing the impact of caregiver deaths critical for pediatric mental health, authors note
The Federal Responses to the Drug Overdose Epidemic
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The twin addiction and overdose crises have collided with the COVID-19 pandemic, each exacerbating the deleterious effects of the other
Preventive Interventions Delivered in Childhood May Reduce Substance Use Over Two Generations
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Children of invervention recipients showed improved developmental functioning before age 5, as well as fewer problem behaviors; better academic, cognitive, and emotional skills; and less risk behavior from ages 6...
Words matter: language can reduce mental health and addiction stigma, NIH leaders say
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Appropriate terminology can improve how people with these conditions are treated in health care settings and society
Emergency department-administered, high-dose buprenorphine may enhance opioid use disorder treatment outcomes
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Study finds treatment is safe and well tolerated in people with opioid use disorder experiencing withdrawal symptoms
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Marijuana use and drinking did not significantly change during the COVID-19 pandemic
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NIH study suggests a link between cannabis use and higher levels of suicidal ideation, plan, and attempt
Using Alcohol and Marijuana Together Exacerbates Negative Consequences in Young Adults
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Simultaneous alcohol and marijuana use is associated with both increased alcohol consumption and greater negative consequences.
Economic Modeling Shows Optimal HIV-Reduction Interventions Depend on the Location
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Researchers identified optimal intervention combinations for six cities (one-quarter of all people with HIV in the U.S.).
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Trial underway to determine whether mobile clinics can help improve health outcomes for people with opioid use disorder
Medication Treatment of Opioid Use Disorder Can Protect Against Overdose Death
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Fewer overdose deaths occurred among adults treated with opioid agonist medications than among those not treated with medication.
Long-lasting medications may improve treatment satisfaction in people with opioid use disorder
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NIH leaders emphasize the importance of patient voices in addiction medication development
Medical records analysis links cannabis use disorder in pregnancy to infant health problems
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Study adds to a growing body of evidence that prenatal exposure to cannabis may be associated with poor birth outcomes
Childhood Caffeine Exposure May Negatively Affect Cognitive Functioning
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For most assessed cognitive functions, the negative correlation remained after controlling for age, gender, socioeconomic status, and sleep.
Study links structural brain changes to behavioral problems in children who snore
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Behavioral problems in children who snore may be associated with changes in the structure of their brain’s frontal lobe
Targeting the Kappa Opioid Receptor to Reduce Drug Use and Relapse
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Inhibition of KORs using a short-acting selective antagonist significantly prevented escalation of cocaine intake in rats during chronic exposure and during re-exposure after withdrawal.
Younger age of first cannabis use or prescription drug misuse is associated with faster development of substance use disorders
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NIH analysis measures the prevalence of nine substance use disorders after first substance use or misuse in young people
Awareness and Use of Pre-Exposure Prophylaxis for HIV Rise in At-Risk Groups, But Not Enough
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Use of pre-exposure prophylaxis to prevent contracting HIV increased among men who have sex with men from 2013 to 2017.
Opioid exposure associated with poppy consumption reported to poison control centers and the U.S. Food and Drug Administration
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Including previously reported cases, there are now at least 19 U.S. deaths associated with poppy seeds in the literature.
Law enforcement seizures of methamphetamine, marijuana rose during pandemic
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Analysis of illegal drug confiscations in five key U.S. regions suggests new drug supply patterns since COVID-19
Using Smartphone Apps to Reach Gay and Bisexual Men at Risk for HIV
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Finding better ways to reach people at higher risk of HIV for testing and engagement with HIV prevention and treatment services is a critical component of a public health response...
Disrupting Cocaine Memories Prevents Return to Cocaine Use in Rats
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Preventing cocaine memories from re-strengthening in an unstable period following retrieval attenuates cocaine seeking.
To end HIV epidemic, we must address health disparities
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Expert report cites unequal progress in Southern U.S. and among marginalized groups
Human Opioid Exposure Can Be Measured Using Wastewater
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Using robotic technology, local levels of opioid metabolites can be measured in wastewater from individual manholes