Dr. Chang has many ongoing research studies, and collaborates extensively with other investigators, on clinical and translational research in neurological complications of HIV and drug abuse. She also leads projects that involve normal and abnormal brain development and brain aging, such as those involved in neonates and children with drug exposure or HIV infection.
The majority of Dr. Chang’s clinical research studies involve the application of advanced neuroimaging techniques to measure brain structure, function and physiology of various neurological diseases. These studies also involve the collection of various clinical specimens (e.g., cerebrospinal fluid, blood and saliva). Her research has been supported by the National Institutes of Health, the Office of National Drug Control Policy and the University of Hawai`i at Mānoa.