Hides, Leanne; Lubman, Dan, I.; Catania, Lisa; Carroll, Steve; Allen, Nicholas; Lambkin, Frances Kay; Baker, Amanda ORYGEN Research Centre, University of Melbourne, Australia/ Centre for Mental Health Studies, University of Newcastle, Australia
Adolescents with a substance use disorder are at two to three times the risk of experiencing concurrent anxiety or mood disorders. While there is a well-established evidence base for the use of CBT in the treatment of depression in young people, the majority of these studies exclude adolescents with drug and alcohol problems, despite increasing evidence for the efficacy of CBT for such problems among young people. More recently, there has been an emphasis on the need for more integrated approaches to the treatment of young people with co-existing depression and substance use problems, and preliminary evidence from two studies has reported positive outcomes for integrated CBT interventions for depression and alcohol dependence in adolescents. The aim of this study was to determine the effectiveness of an integrated cognitive behavior therapy (CBT) intervention for co-occurring depression and substance misuse in young people. Participants consisted of 60 young people aged 15 to 26, with a major depressive disorder and concurrent substance misuse. Participants were provided with 10 sessions of CBT for co-occurring depression and substance misuse and case management over a maximum of 20 weeks. Partial or non responders were provided with a randomized 10-week double-blind, placebo-controlled trial of sertraline. Pre- and post-treatment and 6-month data on depressive and substance use symptoms will be presented. Preliminary results indicated positive outcomes on functioning and depression/anxiety symptoms, but not substance use outcomes post-treatment. Predictors of treatment response to the integrated CBT intervention at mid- and post-treatment will also be reported. Preliminary evidence from recently published pilot studies have demonstrated the efficacy of integrated CBT interventions in alcohol dependent adolescents with co-existing depression. The current paper reports preliminary support for the effectiveness of integrated treatment for depression and substance misuse among young people.