The NIH Common Fund was enacted into law by Congress through the 2006 NIH Reform Act to support cross-cutting, trans-NIH programs that require participation by at least two NIH Institutes or Centers (ICs) or would otherwise benefit from strategic planning and coordination. The requirements for the Common Fund encourage collaboration across the ICs while providing the NIH with flexibility to determine priorities for Common Fund support.
To date, the Common Fund has been used to support a series of short term, exceptionally high impact, trans-NIH programs known collectively as the NIH Roadmap for Medical Research.
The NIH Common Fund is an innovative approach to accelerate fundamental discovery and translation of that knowledge into effective prevention strategies and new treatments. The strategic initiatives to be funded under the NIH Common Fund will address critical roadblocks and knowledge gaps that currently constrain rapid progress in biomedical research. They will synergize the work of many NIH Institutes and Centers, and collectively represent a unique effort that no single or group of Institutes or Centers or other entity can do, but are the responsibility of the NIH as a whole.
New Common Fund Programs
- Global Health - H3 Africa
- HMO Collaboratory
- Program Contact: Sarah Duffy
- Regulatory Science
- Single Cell Analysis
- Protein Capture Reagents
Initiatives and Funding Opportunities
Programs with Ongoing FOA Activity
- Molecular Libraries and Imaging
- Human Microbiome Project
- Genotype-Tissue Expression (GTEx)
- High Risk Research
Clinical Research Training
- Program Contact: Betty Tai
- Program Contact: David J. McCann
- PROMIS (Patient Reported Outcomes Measurements Information Systems)
- National Institutes of Health Rapid Access to Interventional Development (NIH-RAID) Program
- Science of Behavior Change
- Library of Integrates Network-Based Cellular Signatures (LINCS)
- Knockout Mouse Phenotyping
Programs No Longer Soliciting Applications
- Building Blocks, Biological Pathways, and Networks
- Structural Biology
- Interdisciplinary Research
- Bioinformatics and Computational Biology
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Discusses the importance of quality mentorship in drug abuse research and offers suggestions for creating a successful mentor and mentee relationship.