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Image of heroin powder
Photo by DEA

Heroin is an opioid drug made from morphine, a natural substance taken from the seed pod of the various opium poppy plants grown in Southeast and Southwest Asia, Mexico, and Colombia. Heroin can be a white or brown powder, or a black sticky substance known as black tar heroin. Learn about the health effects of heroin and read the DrugFacts.

In 2019, 19.8% of drug overdose deaths involved heroin.

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Clinical trials are research studies in human volunteers conducted to answer specific health questions. Learn about the NIH-sponsored clinical trials available to you.