Hallucinogens are a diverse group of drugs that alter perception (awareness of surrounding objects and conditions), thoughts, and feelings. They cause hallucinations, or sensations and images that seem real though they are not. Hallucinogens can be found in some plants and mushrooms (or their extracts) or can be made by humans. People have used hallucinogens for centuries, mostly for religious rituals. Learn about the health effects of hallucinogens and read the DrugFacts.

Common Names

Ayahuasca, DMT, D-Lysergic Acid Diethylamide (LSD), Peyote (Mescaline), 4-Phosphoryloxy-N,N-Dimethyltryptamine (Psilocybin)

4.6% of high school seniors used hallucinogens in the past year.

Source: 2019 Monitoring the Future Survey

Looking for Treatment?

Other Resources

Clinical Trials

Clinical trials are research studies in human volunteers conducted to answer specific health questions. Learn about the NIH-sponsored clinical trials available to you.