This was a randomized outpatient study for treatment-seeking participants dependent on prescription opioid analgesics. The primary objective was to determine whether the addition of individual drug counseling to the prescription of buprenorphine/naloxone (Bup/Nx) and Standard Medical Management (SMM) improves outcome. Participants were randomized at the beginning of each of two phases to receive BUP/NX paired with either Standard Medical Management (SMM) or Enhanced Medical Management (EMM; defined as SMM plus individual counseling). Six hundred and fifty three participants were randomized into Phase 1, and 360 participants were randomized into Phase 2.
Weiss, et al. (2011). Adjunctive counseling during brief and extended buprenorphine-naloxone treatment for prescription opioid dependence. Archives of General Psychiatry. 68(12):1238-1246.
- Chestnut Ridge Center, West Virginia
- San Francisco General Hospital Division of Substance Abuse and Addiction Medicine (SFGH - DSAAM), California
- Bellevue Hospital Center, New York
- St. Luke's Roosevelt Hospital Center, New York
- McLean Hospital, Massachusetts
- ADAPT, Inc., Oregon
- Providence Regional Medical Center, Behavioral Health Services, Washington
- Integrated Substance Abuse Programs, California
- Behavioral Health Services of Pickens County, South Carolina
- East Indiana Clinic, Indiana
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