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Treatment Research

Brief Description

Drug addiction is a complex illness characterized by intense and sometimes uncontrollable drug craving, along with compulsive drug seeking and use that persist even in the face of devastating consequences. Because drug abuse and addiction have so many dimensions and disrupt so many aspects of a person’s life, treatment is not simple. Scientific research and clinical practice demonstrate the value of behavioral counseling often accompanied by medicines to treat addiction. In addition, continuing care and attention to co-occuring medical problems are important. A variety of approaches having been tested and integrated in residential and community settings. As we look toward the future, we will harness new research results on the influence of genetics and environment on gene function and expression (i.e., epigenetics), which are heralding the development of personalized treatment interventions.

Featured Publications

Publication Cover

Principles of Drug Addiction Treatment: A Research-Based Guide (Third Edition)

Published October 1999. Revised December 2012.
Presents research-based principles of addiction treatment for a variety of drugs, including nicotine, alcohol, and illicit and prescription drugs, that can inform drug treatment programs and services. En Español

Publication Cover

Principles of Drug Abuse Treatment for Criminal Justice Populations - A Research-Based Guide

Published September 2006. Revised January 2012.
Presents research-based principles of addiction treatment that can inform drug treatment programs and services in the criminal justice setting.

Scientist with testtube

Medications Development at NIDA (Topics in Brief)

Revised November 2011.
Offers an update on the research strategy underway in the push to develop effective addiction medications, including currently approved drugs, new compounds, and vaccines.

Related Resources

Other Resources

Past information on many drugs of abuse is available on our Archives site.

This page was last updated December 2012

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    Featured Publication

    Featured Publication

    Drugs, Brains, and Behavior - The Science of Addiction

    As a result of scientific research, we know that addiction is a disease that affects both brain and behavior.

    Blending Initiative

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    Formed with SAMHSA to reduce the gap between research results and treatment.