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NIDA

The Brain & the Actions of Cocaine, Opiates, and Marijuana

14: Summary: THC binding in nucleus accumbens and activation of the reward pathway

THC binding in nucleus accumbens

Show the "big picture." As a result of THC actions in the nucleus accumbens (point to the concentration of THC in the nuc. acc.), there are increased impulses leaving the nucleus accumbens to activate the reward system (point to the frontal cortex). Scientists still don't know how the continued use of marijuana alters the reward system. Indicate that this is an area of intense research by neuroscientists.

This page was last updated January 2007

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NIDA Notes: The Latest in Drug Abuse Research

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