En español
NIDA

Menu

The Brain & the Actions of Cocaine, Opiates, and Marijuana

6: Dopamine and the production of cyclic AMP

Dopamine and the production of cyclic AMP

Using the close-up view, explain what happens when dopamine binds to its receptor. When dopamine binds to its receptor, another protein called a G-protein (in pink) moves up close to the dopamine receptor. The G-protein signals an enzyme to produce cyclic adenosine monophosphate (cAMP) molecules (in green) inside the cell. [Sometimes the signal can decrease production of cAMP, depending on the kind of dopamine receptor and G-protein present.] Point to the dopamine receptor-G-protein/adenylate cyclase complex, and show how cAMP is generated when dopamine binds to its receptor. Indicate that cAMP (point to the cyclic-looking structures) controls many important functions in the cell including the ability of the cell to generate electrical impulses.

This page was last updated January 2007

Cite this article

APA style citation

National Institute on Drug Abuse (2007). 6: Dopamine and the production of cyclic AMP. In The Brain & the Actions of Cocaine, Opiates, and Marijuana. Retrieved from http://www.drugabuse.gov/publications/teaching-packets/brain-actions-cocaine-opiates-marijuana/section-i-introduction-to-brain/6-dopamine-production-c

press ctrl+c to copy

Teaching Packets

Explores the consequences of drug abuse on the brain and body and introduces the topics of prevention, and treatment.