Addiction: A chronic, relapsing disease characterized by compulsive drug seeking and use.
Adulterant: A substance, either a biologically active material such as another drug or an inert material, added to a drug when it is formed into a tablet or capsule.
Cardiovascular system: The heart and blood vessels.
Dopamine: A neurotransmitter present in regions of the brain that regulate movement, emotion, motivation, and the feeling of pleasure.
Ecstasy: Common street name for MDMA.
Gastrointestinal system: The stomach and intestines.
Hyperthermia: A potentially dangerous rise in body temperature.
MDMA: Common chemical name for 3,4-methlyenedioxymethamphetamine.
Neurotransmitter: A chemical that acts as a messenger to carry signals or information from one nerve cell to another.
Norepinephrine: A neurotransmitter present in regions of the brain that affect heart rate and blood pressure.
Serotonin: A neurotransmitter used in widespread parts of the brain, which is involved in sleep, movement and emotions
Tolerance: A decrease in the effect of a drug that occurs with repeated administration.
This series of reports simplifies the science of research findings for the educated lay public, legislators, educational groups, and practitioners. The series reports on research findings of national interest.
Please note: After September 2013 all NIDA Research Reports will be offered online exclusively. Orders for printed hard copies must be received by August 15, 2013.
As a result of scientific research, we know that addiction is a disease that affects both brain and behavior.