Genome wide analyses are being used to identify novel candidate genes that increase the risk for addiction.
This image illustrates convergent findings from different laboratories identifiying a cluster of three nicotinic receptor subunit genes (α3 α5 β4) linked to smoking quantity, nicotine dependence, and the risk of two smoking-related diseases — lung cancer and peripheral arterial disease. This new information on genetic vulnerability also suggests novel targets for the development of medications to treat tobacco addiction and related diseases.
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National Institute on Drug Abuse (July 1 2008). Genome wide analyses are being used to identify novel candidate genes that increase the risk for addiction.. In Addiction Science: From Molecules to Managed Care. Retrieved from http://www.drugabuse.gov/publications/addiction-science/genes-environment-comorbidity/genome-wide-analyses-are-being-used-to-identify-novel-candidate-