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NIDA Notes

image of a brain scan
A prison with an arrow pointing down reading cost and another image of a treatment center with an arrow  pointing up and reading savings
A young Native American mother is playing with her child.
Schematic of the impact of methamphetamine and stress on signal transmission across synapses.

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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Molecular Alterations of DNA Contribute to Persistence of Memory (November 2011)

In a new series of studies tracing the molecular events that occur in the brain as memories are formed and preserved, researchers find that certain epigenetic changes may promote vulnerability to relapse.

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Girls More Likely Than Boys to Use Ecstasy (November 2011)

Lifetime ecstasy use is more prevalent among adolescent girls than among adolescent boys, according to an analysis of 2002–2008 data from the National Survey on Drug Use and Health.

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Resting Brain Studies Shed New Light on Vulnerabilities (November 2011)

Individuals with weak signaling in a nicotine-sensitive brain circuit were more vulnerable to nicotine dependence than those with stronger signaling, according to a study conducted while the subjects’ brains were in a resting state. A second resting-state study finds that the same circuit appears to mediate dependence associated with a genetic risk factor for smoking.

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New Class of Regulators for Addiction Genes (November 2011)

New studies show that microRNAs, snippets of RNA implicated in a wide variety of biological processes, are involved in promoting and inhibiting cocaine addiction. The findings could pave a new path for the development of anti-addiction therapies.

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Good-Bye, Paper (November 2011)

NIDA Notes becomes an All-Web publication in 2012. Issue 2 of Volume 24 will be the last print issue.

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Nanotechnology Powers Smart Skin Patch (November 2011)

An in vitro test demonstrates the potential of a programmable skin patch that will enable physicians to tailor transdermal medication doses to match patients' fluctuating needs.

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Grantee Wins Early Career Award (July 2011)

Announces the 2010 Presidential Early Career Award for Scientists and Engineers to Dr. Mauricio R. Delgado for his work with functional magnetic resonance imaging to investigate how the human brain learns from experiences.

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Gene Influences Impact of Maternal Smoking on Children's Behavioral Problems (July 2011)

Describes research showing that the combination of prenatal smoking exposure and specific genes increases children’s and adolescent’s risk for behavior problems.

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Computer-Based Intervention Offers Good Value for Money (July 2011)

Reports on researchers who demonstrated the economic value of a computer-based treatment as an adjunct to standard addiction therapy.

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Treatment Dropout Linked With Elevated Stress Response (July 2011)

Summarizes a study to determine whether a stress-related biological marker in saliva can predict how long a drug user will remain in treatment.

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