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NIDA Notes

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A prison with an arrow pointing down reading cost and another image of a treatment center with an arrow  pointing up and reading savings
A young Native American mother is playing with her child.
Schematic of the impact of methamphetamine and stress on signal transmission across synapses.

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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Prenatal Cocaine Exposure Increases Monkeys' Impulsivity Into Adulthood (July 2012)

Prenatal drug exposure can have behavioral effects that last well into adulthood, according to two studies of adult monkeys prenatally exposed to cocaine. In the first study, drug-exposed monkeys exhibited less flexibility than controls in adjusting to changing circumstances; in the second study, drug-exposed males exhibited a greater preference than controls for having rewards right away, a sign of impulsivity.

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Program Reduces Recidivism Among Men With Co-occurring Disorders (July 2012)

A modified therapeutic community program designed by NIDA-supported researchers helped Colorado offenders with co-occurring substance use and mental health disorders re-enter their communities and avoid recidivism after release from prison.

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PhenX Toolkit Provides Standard Measures for Research (July 2012)

NIDA researchers working with human subjects now have a new resource at their fingertips: the PhenX Toolkit’s new Substance Abuse and Addiction (SAA) Collection. The Toolkit is designed to provide standardized measures, vetted and approved by the field, to help researchers compare and combine data from multiple studies.

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Adolescent Smoking and Drinking at Historic Lows (July 2012)

Rates of adolescent cigarette smoking and alcohol drinking stood at historic lows in 2011, but marijuana use trended upward, according to the Monitoring the Future (MTF) survey.

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Prevention System Has Lasting Effects, Benefit Exceeds Costs (July 2012)

Towns that implemented a drug abuse prevention program called Communities That Care will see a return of $5.30 for each $1 they invested during the 5-year trial of the intervention, according to a cost-benefit analysis. The estimate is based on reductions in smoking and delinquency observed during the fourth year of the study among eighth-graders and the projected total costs of smoking, delinquency, and crime avoided over the lifetimes of study participants.

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Training Gaps for Evidence-Based Practices (July 2012)

Ninety percent of privately funded substance abuse treatment programs in the United States offer cognitive behavioral therapy (CBT)...

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More Convenient Preparations of Buprenorphine Pass Test (July 2012)

Soluble-film preparations of buprenorphine suppressed heroin abusers’ withdrawal symptoms with no serious side effects in a recent clinical trial. They dissolved more rapidly in the mouth than the pill form of the medication, providing faster relief.

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The Present and Promise of mHealth (July 2012)

NIDA researchers have developed a computer program that motivates and encourages treatment-seeking when an individual is in a primary care physician’s waiting room. Users of the program, called Video Doctor, enter information on a portable device and receive feedback about health risks related to their drug abuse, along with advice, immediately prior to seeing their physician.

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Buprenorphine During Pregnancy Reduces Neonate Distress (July 2012)

Sublingual buprenorphine is a safe and effective alternative to methadone for treating opioid dependence during pregnancy, finds the Maternal Opioid Treatment: Human Experimental Research (MOTHER) study, a NIDA-supported clinical trial. Women who received either medication had similar pregnancy and birth outcomes, but infants born to women who received buprenorphine had milder symptoms of neonatal opioid withdrawal.

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Neuroscience Education Program Encourages Learning at All Ages (July 2012)

Eight scientists have received National Institutes of Health (NIH) grants to develop K-12 education programs that will engage young people in learning about the brain, inspire some to pursue careers in biomedical science, and increase teacher knowledge of neuroscience. The 5-year grants are funded by the NIH Blueprint for Neuroscience Research Science Education.

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