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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Abstinent Patients Continue to Show Benefits of Treatment (April 2007)

Reports on data that reviewing the benefits of addiction treatment among abstinent men as compared with those who continued to abuse cocaine.

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Antipsychotic Drug Prevents Morphine Tolerance in Mice (April 2007)

Summarizes animal studies indicating that an antipsychotic drug, trifluoperazine, prevents morphine tolerance in mice.

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Depot Naltrexone Appears Safe and Effective for Heroin Addiction (April 2007)

Presents results of a pilot study to investigate the safety and efficacy of a new long-lasting injectable formulation of naltrexone to treat of heroin addiction in an outpatient setting.

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Uneven Regional Brain Development Contributes to Adolescent Risk-Taking (April 2007)

Reports on the work of scientists who have linked impulsiveness and risk-taking among adolescents to immaturity of the brain region called the orbitofrontal cortex.

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Incentives Reduce Stimulant Abuse During Methadone Maintenance (April 2007)

Summarizes a study on the use of incentives to encourage abstinence among methadone maintenance patients in outpatient programs.

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Nicotine Alters the Developing Rat Brain (February 2007)

Describes animal studies that suggested exposure to the drug during gestation or adolescence may cause lasting alterations in reward and motivation circuits.

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Medical Care During Addiction Treatment Reduces Hospital Use (February 2007)

Reports on an analysis comparing three types of addiction treatment programs: methadone maintenance programs, long-term residential programs, and nonmethadone programs.

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Cocaine Abusers' Pretreatment Cue Responses Predict Recovery Success (February 2007)

Reports on the work of researchers who used brain images to correlate cocaine-addicted patients' regional brain responses to drug cues with their outcomes in subsequent treatment.

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How Drug Abuse Affects the Brain and Alters Behavior Are Key Questions Driving Division's Work (February 2007)

Discusses the work of NIDA’s Division of Basic Neuroscience and Behavioral Research, the Institute’s locus for studies into the fundamental brain mechanisms underlying drug abuse and addiction.

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Videos Help Treat Deaf People (February 2007)

Reviews a training DVD that presents dialectical behavior therapy skills being taught by deaf clinicians to deaf consumers as an approach to improve deaf people's access to behavioral health care.

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