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NIDA Notes

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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Uneven Regional Brain Development Contributes to Adolescent Risk-Taking (April 2007)

Reports on the work of scientists who have linked impulsiveness and risk-taking among adolescents to immaturity of the brain region called the orbitofrontal cortex.

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Incentives Reduce Stimulant Abuse During Methadone Maintenance (April 2007)

Summarizes a study on the use of incentives to encourage abstinence among methadone maintenance patients in outpatient programs.

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Serotonin System May Have Potential as a Target for Cocaine Medications (April 2007)

Describes investigations to advance the development of potential drug abuse relapse prevention agents by targeting specific receptors of the neurochemical serotonin.

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Genes and Smoking (April 2007)

Reports on the research underway to identify gene variations associated with nicotine addiction and the interaction of genetic makeup, experiences, and surroundings to addiction.

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Nicotine Alters the Developing Rat Brain (February 2007)

Describes animal studies that suggested exposure to the drug during gestation or adolescence may cause lasting alterations in reward and motivation circuits.

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Medical Care During Addiction Treatment Reduces Hospital Use (February 2007)

Reports on an analysis comparing three types of addiction treatment programs: methadone maintenance programs, long-term residential programs, and nonmethadone programs.

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Cocaine Abusers' Pretreatment Cue Responses Predict Recovery Success (February 2007)

Reports on the work of researchers who used brain images to correlate cocaine-addicted patients' regional brain responses to drug cues with their outcomes in subsequent treatment.

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How Drug Abuse Affects the Brain and Alters Behavior Are Key Questions Driving Division's Work (February 2007)

Discusses the work of NIDA’s Division of Basic Neuroscience and Behavioral Research, the Institute’s locus for studies into the fundamental brain mechanisms underlying drug abuse and addiction.

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Videos Help Treat Deaf People (February 2007)

Reviews a training DVD that presents dialectical behavior therapy skills being taught by deaf clinicians to deaf consumers as an approach to improve deaf people's access to behavioral health care.

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Brain Changes Accompany Cocaine Withdrawal (February 2007)

Summarizes an animal study of the neural changes in the amygdala portion of the brain that occur as a result of cocaine exposure followed by withdrawal of the drug.

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