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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Vaccine May Reduce Fetal Exposure to Nicotine (April 2007)

Describes research on a vaccine developed to facilitate smoking cessation by blocking nicotine penetration into the brain.

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Naltrexone-Nicotine Patch Combination Shows Promise (April 2007)

Reports findings from a clinical trial investigating the effectiveness of naltrexone as a supplement to nicotine replacement therapy for smoking cessation.

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Meeting Reviews Progress On Prescription Opioid Misuse (April 2007)

Describes a meeting of researchers and clinicians who gathered to discuss the challenges in balancing appropriate pain treatment with efforts to minimize prescription opioid misuse.

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Standard Treatments Help Depressed Smokers Quit (April 2007)

Describes a study comparing Staged Care Intervention, a combination treatment for smoking cessation, among smokers in outpatient treatment for depression and a control group.

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Interim Methadone Raises Odds of Enrolling in Comprehensive Treatment (April 2007)

Reports on a study to investigate the use of methadone maintenance for heroin addicts wait-listed for a treatment program to encourage their likelihood to enroll in the program.

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Brain Changes Accompany Cocaine Withdrawal (February 2007)

Summarizes an animal study of the neural changes in the amygdala portion of the brain that occur as a result of cocaine exposure followed by withdrawal of the drug.

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Cocaine Craving Activates Brain Reward Structures; Cocaine "High" Dampens Them (February 2007)

Reports on a study that documenting changing emotional and neurobiological responses to cocaine with successive doses during a single session of drug taking.

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GHB Intoxication Reports Decline in California (February 2007)

Highlights statistics on the number of reports of gamma-hydroxybutyrate (GHB) use intoxication in California from 1999 to 2003.

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Journal Highlights Opportunities in Hispanic Drug Abuse Research (February 2007)

Reviews a journal supplement that compiles information on drug abuse research in the Hispanic population.

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Report Calls for Sweeping Changes in Health Care for Mental and Substance Abuse Problems (February 2007)

Reviews a report from the National Academy of Sciences’ Institute of Medicine that discusses ways to improve the quality of health care among people with mental health and substance abuse disorders.

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