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NIDA Notes

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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Chromosome 17 Harbors Opioid Dependence Genes (March 2008)

Describes the work of researchers who have found a statistical link between one region on chromosome 17 and an increased risk of opioid dependence.

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Teen Substance Abuse Continues to Decline (March 2008)

Reports on the prevalence of substance abuse among youth based on 2007 data from a national survey of behaviors, attitudes, and values.

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Not All Mesolimbic Dopamine Neurons Are Alike (March 2008)

Reports on research showing that the neurons that deliver dopamine to two regions of the brain's mesolimbic reward system respond differently to opioids, an important finding for drug treatment research.

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Alcohol Abuse Makes Prescription Drug Abuse More Likely (March 2008)

Reports on results from a study showing that men and women with alcohol use disorders are more likely to report nonmedical use of prescription drugs than people who don't drink at all.

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Cocaine Can Mobilize Stored Dopamine (March 2008)

Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.

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Chronic Cocaine Abusers Have Occult Insomnia in Early Abstinence (March 2008)

Reports on research of chronic cocaine abusers who may feel they are sleeping better during early abstinence revealed that the opposite may be true.

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HIV Patients Show Better Immune Recovery With Early Initiation of HAART (March 2008)

Presents evidence that among men and women with HIV, those who received early initiation of HAART therapy, those with higher CD4+ levels, achieved better immune recovery.

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Exposure to Morphine During Early Adolescence Sensitizes Rats as Adults (October 2007)

Presents highlights of a study indicating that exposure to morphine during adolescence may increase sensitivity to the drug during adulthood.

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Gene Experiment Confirms a Suspected Cocaine Action (October 2007)

Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.

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Among Young Attendees at STD Clinics, Substance Abusers Report More Risky Sexual Behavior (October 2007)

Highlights data on the risky sexual behaviors of patients at a sexually transmitted disease clinic who had a substance abuse disorder as compared to those without a substance abuse disorder.

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