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A prison with an arrow pointing down reading cost and another image of a treatment center with an arrow  pointing up and reading savings
A young Native American mother is playing with her child.
Schematic of the impact of methamphetamine and stress on signal transmission across synapses.

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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Depot Naltrexone Appears Safe and Effective for Heroin Addiction (April 2007)

Presents results of a pilot study to investigate the safety and efficacy of a new long-lasting injectable formulation of naltrexone to treat of heroin addiction in an outpatient setting.

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Uneven Regional Brain Development Contributes to Adolescent Risk-Taking (April 2007)

Reports on the work of scientists who have linked impulsiveness and risk-taking among adolescents to immaturity of the brain region called the orbitofrontal cortex.

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Incentives Reduce Stimulant Abuse During Methadone Maintenance (April 2007)

Summarizes a study on the use of incentives to encourage abstinence among methadone maintenance patients in outpatient programs.

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Serotonin System May Have Potential as a Target for Cocaine Medications (April 2007)

Describes investigations to advance the development of potential drug abuse relapse prevention agents by targeting specific receptors of the neurochemical serotonin.

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Genes and Smoking (April 2007)

Reports on the research underway to identify gene variations associated with nicotine addiction and the interaction of genetic makeup, experiences, and surroundings to addiction.

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Vaccine May Reduce Fetal Exposure to Nicotine (April 2007)

Describes research on a vaccine developed to facilitate smoking cessation by blocking nicotine penetration into the brain.

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Naltrexone-Nicotine Patch Combination Shows Promise (April 2007)

Reports findings from a clinical trial investigating the effectiveness of naltrexone as a supplement to nicotine replacement therapy for smoking cessation.

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Meeting Reviews Progress On Prescription Opioid Misuse (April 2007)

Describes a meeting of researchers and clinicians who gathered to discuss the challenges in balancing appropriate pain treatment with efforts to minimize prescription opioid misuse.

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Standard Treatments Help Depressed Smokers Quit (April 2007)

Describes a study comparing Staged Care Intervention, a combination treatment for smoking cessation, among smokers in outpatient treatment for depression and a control group.

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Interim Methadone Raises Odds of Enrolling in Comprehensive Treatment (April 2007)

Reports on a study to investigate the use of methadone maintenance for heroin addicts wait-listed for a treatment program to encourage their likelihood to enroll in the program.

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