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NIDA Notes

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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Long-Term Cocaine Abuse Linked With Impaired Heart Function (March 2008)

Summarizes research on the effects of long-term regular cocaine abuse on the cardiovascular system in African Americans.

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Scientific Society Honors Dr. Kenner Rice's Research (March 2008)

Announces the 2007 Smissman Award from the American Chemical Society to Dr. Kenner Rice, NIDA, for significant contributions to fundamental knowledge in medicinal chemistry.

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Sertraline Does Not Help Methamphetamine Abusers Quit (March 2008)

Describes a new research finding indicating that the antidepressant sertraline (Zoloft), prescribed to relieve depression during the methamphetamine withdrawal process, may make quitting harder.

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Epigenetics: The Promise of a New Science (March 2008)

Discusses the role of epigenetics, the study of cellular mechanisms that control gene expression and its impacts on health and behavior, in addiction research.

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Bupropion Reduces Meth's Subjective Effects and Cue-Induced Craving (March 2008)

Describes a study investigating the use of the antidepressant bupropion as a potential therapy for methamphetamine addiction.

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Chromosome 17 Harbors Opioid Dependence Genes (March 2008)

Describes the work of researchers who have found a statistical link between one region on chromosome 17 and an increased risk of opioid dependence.

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Neuropeptide Promotes Drug-Seeking and Craving in Rats (October 2007)

Reports on two studies indicating that orexin, a neuropeptide that stimulates eating and regulates wakefulness, also fosters animals' drug seeking and craving responses to drugs.

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Controlling College Students' ADHD Symptoms May Protect Them Against Substance Abuse (October 2007)

Reports data on the prevalence of substance use among college students with ADHD, comparing those who received ADHD treatment with those who did not.

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Endorphin Derivative Inhibits Reward From Morphine and Nicotine in Rats (October 2007)

Describes research investigating a naturally occurring brain chemical that shows early promise as a treatment for addiction in animal studies.

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NIDA's Newest Division Mines Clinical Applications From Basic Research (October 2007)

Describes the role of the Division of Clinical Neuroscience and Behavioral Research in NIDA’s drug abuse and addiction research plan.

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