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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Exposure to Morphine During Early Adolescence Sensitizes Rats as Adults (October 2007)

Presents highlights of a study indicating that exposure to morphine during adolescence may increase sensitivity to the drug during adulthood.

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Gene Experiment Confirms a Suspected Cocaine Action (October 2007)

Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.

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Among Young Attendees at STD Clinics, Substance Abusers Report More Risky Sexual Behavior (October 2007)

Highlights data on the risky sexual behaviors of patients at a sexually transmitted disease clinic who had a substance abuse disorder as compared to those without a substance abuse disorder.

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Adolescent Inhalant Use Is Stable Overall, but Rising Among Girls (October 2007)

Reports patterns and trends in inhalant use among adolescents based on an analysis of data from a 2002-2005 national survey on drug use and health.

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Study Links Anabolic Steroids to Brain Changes in Adolescent Female Mice (October 2007)

Reports on an animal study finding that links anabolic steroids to brain changes in adolescent female mice, changes that can potentially lead to steroid abuse.

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Impacts of Drugs on Neurotransmission (October 2007)

Discusses the central importance of studying drugs' effects on neurotransmission and describes some of the most common experimental methods used in this research.

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Tracing NET (October 2007)

Describes research that has led to the development of a new tool, a new radiotracer, for studying the neurobiology of depression, attention deficit hyperactivity disorder, and stimulant abuse.

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Uneven Regional Brain Development Contributes to Adolescent Risk-Taking (April 2007)

Reports on the work of scientists who have linked impulsiveness and risk-taking among adolescents to immaturity of the brain region called the orbitofrontal cortex.

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Incentives Reduce Stimulant Abuse During Methadone Maintenance (April 2007)

Summarizes a study on the use of incentives to encourage abstinence among methadone maintenance patients in outpatient programs.

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Serotonin System May Have Potential as a Target for Cocaine Medications (April 2007)

Describes investigations to advance the development of potential drug abuse relapse prevention agents by targeting specific receptors of the neurochemical serotonin.

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