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NIDA Notes

image of a brain scan
A prison with an arrow pointing down reading cost and another image of a treatment center with an arrow  pointing up and reading savings
A young Native American mother is playing with her child.
Schematic of the impact of methamphetamine and stress on signal transmission across synapses.

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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Endorphin Derivative Inhibits Reward From Morphine and Nicotine in Rats (October 2007)

Describes research investigating a naturally occurring brain chemical that shows early promise as a treatment for addiction in animal studies.

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NIDA's Newest Division Mines Clinical Applications From Basic Research (October 2007)

Describes the role of the Division of Clinical Neuroscience and Behavioral Research in NIDA’s drug abuse and addiction research plan.

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Exposure to Morphine During Early Adolescence Sensitizes Rats as Adults (October 2007)

Presents highlights of a study indicating that exposure to morphine during adolescence may increase sensitivity to the drug during adulthood.

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Gene Experiment Confirms a Suspected Cocaine Action (October 2007)

Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.

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Among Young Attendees at STD Clinics, Substance Abusers Report More Risky Sexual Behavior (October 2007)

Highlights data on the risky sexual behaviors of patients at a sexually transmitted disease clinic who had a substance abuse disorder as compared to those without a substance abuse disorder.

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Adolescent Inhalant Use Is Stable Overall, but Rising Among Girls (October 2007)

Reports patterns and trends in inhalant use among adolescents based on an analysis of data from a 2002-2005 national survey on drug use and health.

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Antipsychotic Drug Prevents Morphine Tolerance in Mice (April 2007)

Summarizes animal studies indicating that an antipsychotic drug, trifluoperazine, prevents morphine tolerance in mice.

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Depot Naltrexone Appears Safe and Effective for Heroin Addiction (April 2007)

Presents results of a pilot study to investigate the safety and efficacy of a new long-lasting injectable formulation of naltrexone to treat of heroin addiction in an outpatient setting.

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Uneven Regional Brain Development Contributes to Adolescent Risk-Taking (April 2007)

Reports on the work of scientists who have linked impulsiveness and risk-taking among adolescents to immaturity of the brain region called the orbitofrontal cortex.

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