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image of a brain scan
A prison with an arrow pointing down reading cost and another image of a treatment center with an arrow  pointing up and reading savings
A young Native American mother is playing with her child.
Schematic of the impact of methamphetamine and stress on signal transmission across synapses.

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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Sertraline Does Not Help Methamphetamine Abusers Quit (March 2008)

Describes a new research finding indicating that the antidepressant sertraline (Zoloft), prescribed to relieve depression during the methamphetamine withdrawal process, may make quitting harder.

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Epigenetics: The Promise of a New Science (March 2008)

Discusses the role of epigenetics, the study of cellular mechanisms that control gene expression and its impacts on health and behavior, in addiction research.

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Bupropion Reduces Meth's Subjective Effects and Cue-Induced Craving (March 2008)

Describes a study investigating the use of the antidepressant bupropion as a potential therapy for methamphetamine addiction.

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Journal Highlights Global Nexus of Drug Abuse and HIV/AIDS (October 2007)

Reviews a journal supplement that compiles studies on drug-related HIV transmission, with a focus on injection drug use, in 16 different localities across the globe.

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Neuropeptide Promotes Drug-Seeking and Craving in Rats (October 2007)

Reports on two studies indicating that orexin, a neuropeptide that stimulates eating and regulates wakefulness, also fosters animals' drug seeking and craving responses to drugs.

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Controlling College Students' ADHD Symptoms May Protect Them Against Substance Abuse (October 2007)

Reports data on the prevalence of substance use among college students with ADHD, comparing those who received ADHD treatment with those who did not.

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Endorphin Derivative Inhibits Reward From Morphine and Nicotine in Rats (October 2007)

Describes research investigating a naturally occurring brain chemical that shows early promise as a treatment for addiction in animal studies.

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NIDA's Newest Division Mines Clinical Applications From Basic Research (October 2007)

Describes the role of the Division of Clinical Neuroscience and Behavioral Research in NIDA’s drug abuse and addiction research plan.

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Exposure to Morphine During Early Adolescence Sensitizes Rats as Adults (October 2007)

Presents highlights of a study indicating that exposure to morphine during adolescence may increase sensitivity to the drug during adulthood.

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