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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Cocaine Locks Rats Into Unrewarding Behaviors (April 2009)

Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.

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High School Seniors Report Alcohol- or Drug-Impaired Driving Experiences (April 2009)

Examines the incidence of high school seniors’ alcohol- or drug-related driving experiences based on 2001 through 2006 data.

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Methamphetamine Abusers Show Increased Distractibility (April 2009)

Highlights findings from a study of former methamphetamine abusers showing evidence of impairment in areas of the brain known to influence cognition, emotion, and decision making.

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Reducing Postpartum Drug Use (December 2008)

Highlights a computerized intervention that reduced new mothers' drug abuse in the first 4 months postpartum as reported in a clinical trial of 107 women who abused drugs.

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High-Risk Drug Offenders Do Better With Close Judicial Supervision (December 2008)

Reports on research showing that increasing the mandatory drug court monitoring sessions for high-risk drug offenders can enhance program success rates.

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Nicotine Dependence is Linked With Mental Disorders in Pregnant Women (December 2008)

Reports on a link between mental disorders, including mood, anxiety, or personality disorder and nicotine dependence in pregnancy women.

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Aripiprazole Prevents Rats From Resuming Cocaine Seeking (December 2008)

Reports on study results indicating a medication prescribed for schizophrenia and manic phases of bipolar disorder shows promise as a cocaine addiction treatment.

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Lofexidine May Enhance Naltrexone Efficacy (December 2008)

Highlights results from a pilot study suggesting that lofexidine, an anti-hypertensive medication, can enhance success rates among patients taking maintenance naltrexone to avoid opioid relapse.

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Imaging Studies Elucidate Neurobiology of Cigarette Craving (December 2008)

Reports on three separate imaging studies illuminating the neurobiology of cigarette craving.

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Selenium Shows Promise as an Adjunct Therapy for HIV (December 2008)

Reports on a randomized controlled trial of HIV-infected men and women who, as a result of receiving selenium supplements, experienced lower HIV viral load and greater CD4 cell count.


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