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NIDA Notes

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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Aripiprazole Prevents Rats From Resuming Cocaine Seeking (December 2008)

Reports on study results indicating a medication prescribed for schizophrenia and manic phases of bipolar disorder shows promise as a cocaine addiction treatment.

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Lofexidine May Enhance Naltrexone Efficacy (December 2008)

Highlights results from a pilot study suggesting that lofexidine, an anti-hypertensive medication, can enhance success rates among patients taking maintenance naltrexone to avoid opioid relapse.

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Imaging Studies Elucidate Neurobiology of Cigarette Craving (December 2008)

Reports on three separate imaging studies illuminating the neurobiology of cigarette craving.

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Selenium Shows Promise as an Adjunct Therapy for HIV (December 2008)

Reports on a randomized controlled trial of HIV-infected men and women who, as a result of receiving selenium supplements, experienced lower HIV viral load and greater CD4 cell count.

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New Technique Links 89 Genes to Drug Dependence (September 2008)

Presents research findings linking 89 genes to drug abuse and dependence, found using genome-wide association studies, a new technique for identifying genes.

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Research Breakthroughs in Drug Abuse Have Wide Applications in Other Fields (September 2008)

Offers an overview of some of the NIDA-supported innovative research achievements to reduce the health and social effects of drug abuse and addiction.

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Immune System Plays Unexpected Role in Brain Development (September 2008)

Describes research findings demonstrating that the immune system participates in the shaping of brain circuits during a child's development, a finding that may shed light on the origins of neurodegenerative diseases.

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Basic Science Discoveries Yield Novel Approaches to Analgesia (September 2008)

Describes research to develop new compounds that match or exceed the pain relief provided by opioids while avoiding their shortcomings.

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Optical Technologies Expand Vistas Into the Brain (September 2008)

Describes new tools under development, including one to visualize cells deep in the brain and another one that remotely activates brain cells.

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NIDA Bestows Prizes at International Science Fair (September 2008)

Announces the three winners of the NIDA and Scholastic Corporation 2008 Addiction Science Awards honoring high school students’ award-winning addiction-related projects.

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