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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Long-Term Cocaine Self-Administration Depresses Brain Activity (December 2008)

Discusses research exploring how widespread the reduction of neural activity is in the brain with chronic exposure to cocaine.

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Brain Proteins Differ in Cocaine-Overdose Victims (December 2008)

Describes research findings showing differences in protein concentrations in the brain pleasure centers of people who died from cocaine overdose as compared with those who did not abuse the drug.

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New Vaccines Are Being Developed Against Addiction and Relapse (December 2008)

Highlights NIDA-funded research to develop vaccines against addiction to drugs such as cocaine, nicotine, phencyclidine (PCP), and methamphetamine.

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Henry Yamamura Obituary (December 2008)

Remembers Henry I. "Hank" Yamamura, an eminent neuropharmacologist who pioneered radioligand binding assays, contributing valuable knowledge about neurotransmitter transporters and receptors.

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Methadone Reduces Rats' Cocaine Seeking (December 2008)

Reports on an animal study showing that methadone, normally used as a therapy for opioid abuse, may prove to be an effective treatment for cocaine abuse.

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Reducing Postpartum Drug Use (December 2008)

Highlights a computerized intervention that reduced new mothers' drug abuse in the first 4 months postpartum as reported in a clinical trial of 107 women who abused drugs.

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High-Risk Drug Offenders Do Better With Close Judicial Supervision (December 2008)

Reports on research showing that increasing the mandatory drug court monitoring sessions for high-risk drug offenders can enhance program success rates.

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Nicotine Dependence is Linked With Mental Disorders in Pregnant Women (December 2008)

Reports on a link between mental disorders, including mood, anxiety, or personality disorder and nicotine dependence in pregnancy women.

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Aripiprazole Prevents Rats From Resuming Cocaine Seeking (December 2008)

Reports on study results indicating a medication prescribed for schizophrenia and manic phases of bipolar disorder shows promise as a cocaine addiction treatment.

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NIDA Bestows Prizes at International Science Fair (September 2008)

Announces the three winners of the NIDA and Scholastic Corporation 2008 Addiction Science Awards honoring high school students’ award-winning addiction-related projects.

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