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NIDA Notes

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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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NIDA Initiates Pediatrics Symposium on Adolescent Health (April 2009)

Presents highlights of a symposium sponsored by NIDA in October 2008 to discuss adolescent brain and cognitive development and consider the impact of drug abuse on young people.

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Adolescent Rats Self-Administer More Nicotine Than Adults (April 2009)

Highlights an animal study involving the self-administration of nicotine among adolescent and adult rats to gain understanding of their potential vulnerability to the substance.

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Low Dopamine Receptor Availability May Promote Cocaine Addiction (April 2009)

Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.

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Prenatal Nicotine Exposure May Damage Receptors That Influence Auditory Processing (April 2009)

Reports on a series of animal experiments indicating that nicotine exposure during prenatal fetal development damages a set of receptors in the brain's auditory processing center.

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Cocaine Locks Rats Into Unrewarding Behaviors (April 2009)

Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.

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Reducing Postpartum Drug Use (December 2008)

Highlights a computerized intervention that reduced new mothers' drug abuse in the first 4 months postpartum as reported in a clinical trial of 107 women who abused drugs.

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High-Risk Drug Offenders Do Better With Close Judicial Supervision (December 2008)

Reports on research showing that increasing the mandatory drug court monitoring sessions for high-risk drug offenders can enhance program success rates.

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Nicotine Dependence is Linked With Mental Disorders in Pregnant Women (December 2008)

Reports on a link between mental disorders, including mood, anxiety, or personality disorder and nicotine dependence in pregnancy women.

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Aripiprazole Prevents Rats From Resuming Cocaine Seeking (December 2008)

Reports on study results indicating a medication prescribed for schizophrenia and manic phases of bipolar disorder shows promise as a cocaine addiction treatment.

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Lofexidine May Enhance Naltrexone Efficacy (December 2008)

Highlights results from a pilot study suggesting that lofexidine, an anti-hypertensive medication, can enhance success rates among patients taking maintenance naltrexone to avoid opioid relapse.

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