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NIDA Notes

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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Receptor Complexes Link Dopamine to Long-Term Neuronal Effects (October 2009)

Reports on a discovery of previously unrecognized dopamine receptors in the brain that when triggered by drug abuse lead to potentially long-term neuronal effects.

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Combined Treatments Improve Dual Abstinence (October 2009)

Reports on a study investigating the effectiveness of a combined therapy of disulfiram and naltrexone for people who abuse cocaine and alcohol.

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Intervention for Disruptive Children Shows Long-Term Benefits (October 2009)

Reports on research providing evidence that teaching aggressive youngsters social coping skills reduces their chances of becoming substance abusers.

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New Tracer for Nicotinic Receptors Promises Improved Specificity (April 2009)

Reports on NIDA researchers who developed a new tracer compound that binds readily to nicotine receptors and enhances positron emission tomography images.

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Stimulus Money Will Fund a Surge in Knowledge (April 2009)

Describes NIDA’s drug abuse and addiction research priorities for the use of the American Recovery and Reinvestment Act of 2009 funds.

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Legal Pressure Increases Treatment Retention (April 2009)

Presents data on the length of stay in substance abuse treatment among people who were in treatment as a result of legal pressure as compared with those in treatment voluntarily.

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NIDA Initiates Pediatrics Symposium on Adolescent Health (April 2009)

Presents highlights of a symposium sponsored by NIDA in October 2008 to discuss adolescent brain and cognitive development and consider the impact of drug abuse on young people.

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Adolescent Rats Self-Administer More Nicotine Than Adults (April 2009)

Highlights an animal study involving the self-administration of nicotine among adolescent and adult rats to gain understanding of their potential vulnerability to the substance.

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Low Dopamine Receptor Availability May Promote Cocaine Addiction (April 2009)

Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.

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Prenatal Nicotine Exposure May Damage Receptors That Influence Auditory Processing (April 2009)

Reports on a series of animal experiments indicating that nicotine exposure during prenatal fetal development damages a set of receptors in the brain's auditory processing center.

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