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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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High-Risk Drug Offenders Do Better With Close Judicial Supervision (December 2008)

Reports on research showing that increasing the mandatory drug court monitoring sessions for high-risk drug offenders can enhance program success rates.

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Nicotine Dependence is Linked With Mental Disorders in Pregnant Women (December 2008)

Reports on a link between mental disorders, including mood, anxiety, or personality disorder and nicotine dependence in pregnancy women.

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Aripiprazole Prevents Rats From Resuming Cocaine Seeking (December 2008)

Reports on study results indicating a medication prescribed for schizophrenia and manic phases of bipolar disorder shows promise as a cocaine addiction treatment.

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Lofexidine May Enhance Naltrexone Efficacy (December 2008)

Highlights results from a pilot study suggesting that lofexidine, an anti-hypertensive medication, can enhance success rates among patients taking maintenance naltrexone to avoid opioid relapse.

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Imaging Studies Elucidate Neurobiology of Cigarette Craving (December 2008)

Reports on three separate imaging studies illuminating the neurobiology of cigarette craving.

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Selenium Shows Promise as an Adjunct Therapy for HIV (December 2008)

Reports on a randomized controlled trial of HIV-infected men and women who, as a result of receiving selenium supplements, experienced lower HIV viral load and greater CD4 cell count.

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NIDA Centers Raise Physicians' Awareness of Drug Abuse Issues (December 2008)

Highlights four Centers of Excellence for Physician Information designed to increase physicians' awareness of research on the medical consequences of drug abuse and addiction and incorporate research findings into clinical practice.

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Fewer Young Adults Abuse Cocaine and Methamphetamine, National Survey Finds (December 2008)

Reports prevalence rates of illicit drug abuse among youths and young adults based on 2007 data from a national survey of drug use and health.

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Long-Term Cocaine Self-Administration Depresses Brain Activity (December 2008)

Discusses research exploring how widespread the reduction of neural activity is in the brain with chronic exposure to cocaine.

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Brain Proteins Differ in Cocaine-Overdose Victims (December 2008)

Describes research findings showing differences in protein concentrations in the brain pleasure centers of people who died from cocaine overdose as compared with those who did not abuse the drug.

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