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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Abstinent Smokers' Nicotinic Receptors Take More Than a Month to Normalize (October 2009)

Describes research revealing that for up to 6 weeks after smokers quit, their brain cells have more nicotine-binding receptors than nonsmokers, which may explain the struggle to quit.

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Drug Cues Outside Awareness Rapidly Trigger Brain's Emotion Centers (October 2009)

Describes research showing that cocaine abusers appear to have a rapid neural response to reward cues outside of their awareness, possibly signifying vulnerability to relapse.

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Manic Mice Show Heightened Sensitivity to Rewards (October 2009)

Reports on an animal study suggesting that the manic stage of bipolar disorder promotes signs of drug abuse vulnerability by enhancing sensitivity to rewards, both natural and drug-related.

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Lower Rates of Cigarette and Marijuana Smoking Among Exercising Teens (October 2009)

Highlights prevalence rates of cigarette and marijuana smoking among teens who exercise regularly as compared with their less active peers.

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Three Scientists Receive Grants for Innovative AIDS Research (October 2009)

Announces the recipients of the inaugural Avant-Garde Award for research to prevent and treat HIV/AIDS in drug abusers, Drs. Julio Montaner, Ileana Cristea, and Jerome Groopman.

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Suiting Treatment to the Nature of the Disease (October 2009)

Highlights NIDA-sponsored research underway to understand and respond to substance abusers’ needs at all points of care, from the initial presentation for treatment through recovery.

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Sensory Aspects of Smoking May Counter Bad Mood, Craving (October 2009)

Describes study findings revealing that the act of smoking, apart from actual or expected nicotine delivery, may soothe a smoker's negative mood.

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Program Reduces Girls' Delinquent Behavior (October 2009)

Reports on a study involving adolescent girls who were treated for delinquent behaviors in a well-supervised family setting, referred to as Multidimensional Treatment Foster Care.

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Conferees Discuss Ways to Eliminate Disparities in Care (October 2009)

Presents highlights of a meeting summit to discuss ways to eliminate disparities in care, particularly as they relate to drug abuse and HIV.

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Ethnic Groups Have Contrasting Genetic Risks for Nicotine Addiction (October 2009)

Describes research exploring differences and similarities in the genetic profiles of African-Americans and European-Americans who are heavy smokers.

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