NIDA Notes Articles: cocaine

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Tobacco Smokers Have High Probability of Transition to Dependence

April 2012
First-time smokers have a much higher chance of eventually becoming dependent than first-time users alcohol, cannabis, and cocaine.

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Physical Activity Reduces Return to Cocaine Seeking in Animal Tests

April 2012
Two independent animal studies suggest that aerobic exercise might help cocaine abusers establish and maintain abstinence.

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Program Helps Troubled Boys Reduce Substance Abuse

December 2011
Chronically delinquent boys in Multidimensional Treatment Foster Care reduced their substance abuse more than boys assigned to Community Group Care.

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Stimulant Abusers' Regard for Future Improves With Memory Training

December 2011
Researchers correlate stimulant abusers’ improved performance on a memory training exerc ise with reductions in delay discounting.

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Disruption of Neuron Production in Adult Rats Increases Cocaine Taking

November 2011
Drug abuse may diminish production of new neurons in the brain’s hippocampus and thereby increase vulnerability to drug addiction.

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Neuropeptide Promotes Behaviors Tied to Addiction and Overeating

July 2011
Reports on several studies implicating a certain neuropeptide (a signaling molecule) in fostering addition and overeating and discusses implications for addiction treatment.

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Cocaine Alters Production of Hundreds of Proteins

March 2011
Describes research findings that show that chronic cocaine abuse may change the production of many proteins in the neurons of the brain’s reward system, aiding in our understanding how the drug causes addiction.

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Dr. Paul Kenny Receives the 2010 Waletzky Memorial Award

March 2011
Announces the recipient of a 2010 award for innovation in research on drug addiction and alcoholism and describes his work on increasing our understanding of the molecular foundation of addiction.

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Cocaine Vaccine Helps Some Reduce Drug Abuse

December 2010
Reports on the results of a clinical trial that tested the effectiveness of a cocaine vaccine designed as a therapy for cocaine abuse and plans underway for a new study of 300 patients to confirm these results.

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Incentives Promote Abstinence

December 2010
Explores research findings on the value of motivational incentives to promote and reinforce abstinence from substances of abuse and encourage healthy behaviors.

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