December 2009
Reports findings that a rare neuroreceptor may be linked to the intensive cravings cocaine abusers experience during their first weeks of abstinence.

Test Substance Attenuates Signs of Cocaine Withdrawal in Rats

December 2009
Reports on several drugs that may ward off depression and anxiety, common withdrawal symptoms from cocaine, based on an animal study.

Patch Delivers Buprenorphine for Heroin Detox

November 2009
Describes research on the effectiveness of a buprenorphine patch to alleviate opioid withdrawal symptoms of newly abstinent heroin abusers.

Lofexidine May Enhance Naltrexone Efficacy

December 2008
Highlights results from a pilot study suggesting that lofexidine, an anti-hypertensive medication, can enhance success rates among patients taking maintenance naltrexone to avoid opioid relapse.

Sertraline Does Not Help Methamphetamine Abusers Quit

March 2008
Describes a new research finding indicating that the antidepressant sertraline (Zoloft), prescribed to relieve depression during the methamphetamine withdrawal process, may make quitting harder.

Brain Changes Accompany Cocaine Withdrawal

February 2007
Summarizes an animal study of the neural changes in the amygdala portion of the brain that occur as a result of cocaine exposure followed by withdrawal of the drug.

Study Finds Withdrawal No Easier With Ultrarapid Opiate Detox

October 2006
Presents findings from a clinical trial comparing ultrarapid, anesthesia-assisted detoxification with detoxification by traditional methods among patients addicted to heroin.

NIDA Notes Articles: Withdrawal

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