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NIDA Notes Articles

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Booklet Explains the Science of Addiction

June 2008

Describes a booklet that explains what scientists know about how drug addiction changes the brain and affects behavior and clears up misconceptions about drug addiction.

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Mice With Genetic Alteration Eschew Cocaine

June 2008

Reports on a study involving researchers who successfully desensitized mice to cocaine by genetically altering their dopamine transporters.

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Intervention Improves Employment Outlook For Methadone Patients

June 2008

Describes a study of unemployed methadone patients and the use of assertive outreach and motivational techniques to improve the patients’ employment outlook.

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Behavioral Problems Related to Maternal Smoking During Pregnancy Manifest Early in Childhood

June 2008

Describes research providing evidence that maternal smoking during pregnancy contributes to behavioral conduct disorders among toddlers, school-age children, and teens.

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Morphine-Induced Immunosuppression, From Brain to Spleen

June 2008

Reports on scientists who pinpointed the biochemical trigger from morphine that sets off a chain reaction that inhibits an immune cell that is key in fighting viruses and cancer.

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Animal Studies Elaborate Toluene's Effects

June 2008

Reports on evidence that toluene abuse can harm the nervous system and body, although scientists know relatively little about its specific actions.

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Cocaine Can Mobilize Stored Dopamine

March 2008

Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.

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Chronic Cocaine Abusers Have Occult Insomnia in Early Abstinence

March 2008
Reports on research of chronic cocaine abusers who may feel they are sleeping better during early abstinence revealed that the opposite may be true.

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HIV Patients Show Better Immune Recovery With Early Initiation of HAART

March 2008
Presents evidence that among men and women with HIV, those who received early initiation of HAART therapy, those with higher CD4+ levels, achieved better immune recovery.

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Researchers Report on Progress of NIDA's Southern Africa Initiative

March 2008
Presents an update on NIDA’s Southern African Initiative, a program that aims to build research capacity and infrastructure in the area of addiction, particularly drug-related HIV transmission.

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