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NIDA Notes Articles: Treatment Research

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Physical Activity Reduces Return to Cocaine Seeking in Animal Tests

April 2012

Two independent animal studies suggest that aerobic exercise might help cocaine abusers establish and maintain abstinence.

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Women and Sex/Gender Differences Research Program

April 2012
NIDA’s Women and Sex/Gender Differences Research Program focuses on gender-specific addiction risk factors and treatment needs.

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Antiretroviral Treatment Reduces Spread of HIV Among Injection Drug Users

April 2012
Expanded use of antiretroviral therapy in British Columbia reduced the spread of HIV among injection drug users and others in the province.

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Cognitive Strategy Reduces Craving by Altering Brain Activity

April 2012

While viewing images of cigarettes, smokers reported milder cravings when they shifted their focus from the pleasures of smoking to its harmful effects. Brain imaging showed a correlation between the reductions in craving and altered activity levels in regions associated with emotional regulation and reward.

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NIDA Announces Avant-Garde Medication Development Awards

March 2012
Dr. Thomas Kosten of Baylor College of Medicine and Dr. Peter Burkhard of the University of Connecticut are the recipients of NIDA’s 2011 Avant-Garde Awards for Innovative Medication Development Research. Dr. Kosten is developing a vaccine against methamphetamine abuse and Dr. Burkhard is developing a vaccine to counter nicotine addiction.

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In Animals, Receptor Puts Brakes on Nicotine Consumption

March 2012

New research suggests that differences in tobacco consumption reflect, in part, differences in the functional efficacy of a specific type of receptor in a pathway of the brain. In animal studies, nicotinic acetylcholine receptors with the α5 subunit played a key role in producing aversive responses to nicotine, thereby dissuading further consumption of the drug.

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Financial Strain Hinders Smoking Cessation

December 2011

Helping smokers deal with financial problems could improve their chances of staying abstinent after receiving treatment, according to a new study. Participants with the most financial strain had the least success in remaining abstinent.

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Stimulant Abusers' Regard for Future Improves With Memory Training

December 2011
Researchers correlate stimulant abusers’ improved performance on a memory training exerc ise with reductions in delay discounting.

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New Class of Regulators for Addiction Genes

November 2011
New studies show that microRNAs, snippets of RNA implicated in a wide variety of biological processes, are involved in promoting and inhibiting cocaine addiction. The findings could pave a new path for the development of anti-addiction therapies.

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Nanotechnology Powers Smart Skin Patch

November 2011
An in vitro test demonstrates the potential of a programmable skin patch that will enable physicians to tailor transdermal medication doses to match patients' fluctuating needs.

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