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NIDA Notes Articles

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Brain Opioid Receptor Levels Predict Time to Cocaine Relapse

October 2010
Describes study findings revealing that cocaine abusers who maintain high levels of a certain receptor in their brain during early abstinence relapse sooner than abusers whose levels drop.

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Brain Adaptation May Dampen Effects of Cocaine

October 2010
Reports evidence that a cocaine-induced change in the structure of brain cells represents an adaptive response that may limit the drug’s impact.

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Neuroimaging Challenges Common Assumption of Public Service Messaging

October 2010
Describes a study of smokers' brain function while they watched antismoking PSAs and findings suggesting that calmer ads may be more effective.

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French Government Honors Dr. Volkow

October 2010
Announces the 2009 International Prize, awarded by the French Institute of Health and Medical Research, to NIDA Director Dr. Nora D. Volkow.

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Lower Levels of Dopamine-Regulating Receptors Among Novelty Seekers

October 2010

Describes research results reporting that people who favor novelty have lower-than-average availability of a receptor that inhibits dopamine's release from neurons, which likely stimulates the activity of reward circuits.

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Crack Cocaine Promotes Progression of HIV Infection to AIDS

October 2010
Reports on two studies showing a high prevalence of HIV infection and more rapid progression to disability and death among drug abusers.

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Young Opioid Abusers Benefit From Extended Buprenorphine-Naloxone Treatment

April 2010
Reports on a study investigating the benefits of extended opioid maintenance therapy that included drug counseling and 12 weeks of therapy with buprenorphine and naloxone.

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Injection Drug Users Acquire Hepatitis C Infection Later in Developed Countries

April 2010
Reports trends in onset of injection drug use to infection with hepatitis C virus in developed countries and notes the influence of prevention efforts.

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Attention to Bipolar Disorder Strengthens Substance Abuse Treatment

April 2010

Describes a study of participants who had both substance abuse and bipolar disorder to investigate the potential benefits of integrated group therapy for this population.

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Genetic Overlap Between Substance Abuse and Bipolar Disorder

April 2010

Describes a literature analysis reporting on the prevalence of people with bipolar disorder who also have a substance use disorder and discusses the genetic link that may contribute to this comorbidity.

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