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NIDA Notes Articles

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Depot Naltrexone Appears Safe and Effective for Heroin Addiction

April 2007
Presents results of a pilot study to investigate the safety and efficacy of a new long-lasting injectable formulation of naltrexone to treat of heroin addiction in an outpatient setting.

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Uneven Regional Brain Development Contributes to Adolescent Risk-Taking

April 2007

Reports on the work of scientists who have linked impulsiveness and risk-taking among adolescents to immaturity of the brain region called the orbitofrontal cortex.

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Incentives Reduce Stimulant Abuse During Methadone Maintenance

April 2007

Summarizes a study on the use of incentives to encourage abstinence among methadone maintenance patients in outpatient programs.

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Studies Focus on Acculturation and Hispanic Youth

February 2007
Summarizes a study that analyzes factors associated with the risk of drug addiction among 19- to 21-year-old Hispanic women born in the United States as compared with immigrants.

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Behavioral Response to Novelty Foreshadows Neurological Response to Cocaine

February 2007
Describes evidence supporting the view that developmental differences in brain systems that use the neurotransmitter dopamine underlie age differences in susceptibility to drug abuse.

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Nicotine Alters the Developing Rat Brain

February 2007
Describes animal studies that suggested exposure to the drug during gestation or adolescence may cause lasting alterations in reward and motivation circuits.

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Medical Care During Addiction Treatment Reduces Hospital Use

February 2007
Reports on an analysis comparing three types of addiction treatment programs: methadone maintenance programs, long-term residential programs, and nonmethadone programs.

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Cocaine Abusers' Pretreatment Cue Responses Predict Recovery Success

February 2007
Reports on the work of researchers who used brain images to correlate cocaine-addicted patients' regional brain responses to drug cues with their outcomes in subsequent treatment.

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How Drug Abuse Affects the Brain and Alters Behavior Are Key Questions Driving Division's Work

February 2007
Discusses the work of NIDA’s Division of Basic Neuroscience and Behavioral Research, the Institute’s locus for studies into the fundamental brain mechanisms underlying drug abuse and addiction.

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Videos Help Treat Deaf People

February 2007
Reviews a training DVD that presents dialectical behavior therapy skills being taught by deaf clinicians to deaf consumers as an approach to improve deaf people's access to behavioral health care.

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