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NIDA
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Receptor Complexes Link Dopamine to Long-Term Neuronal Effects

October 2009

Reports on a discovery of previously unrecognized dopamine receptors in the brain that when triggered by drug abuse lead to potentially long-term neuronal effects.

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Combined Treatments Improve Dual Abstinence

October 2009

Reports on a study investigating the effectiveness of a combined therapy of disulfiram and naltrexone for people who abuse cocaine and alcohol.

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Intervention for Disruptive Children Shows Long-Term Benefits

October 2009

Reports on research providing evidence that teaching aggressive youngsters social coping skills reduces their chances of becoming substance abusers.

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Smoking and Drinking Continue to Decline, But Marijuana Stalls in Latest MTF Survey

October 2009

Highlights trends from a 2008 survey of teenage substance abuse, cigarette smoking and alcohol use and discusses the implications of these changing data.

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NIDA Reprises Online Chat Day

October 2009

Highlights NIDA’s second annual Chat Day where NIDA scientists and staff responded to drug abuse and addiction questions from teachers and students.

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Abstinent Smokers' Nicotinic Receptors Take More Than a Month to Normalize

October 2009

Describes research revealing that for up to 6 weeks after smokers quit, their brain cells have more nicotine-binding receptors than nonsmokers, which may explain the struggle to quit.

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Drug Cues Outside Awareness Rapidly Trigger Brain's Emotion Centers

October 2009

Describes research showing that cocaine abusers appear to have a rapid neural response to reward cues outside of their awareness, possibly signifying vulnerability to relapse.

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Adolescent Rats Self-Administer More Nicotine Than Adults

April 2009

Highlights an animal study involving the self-administration of nicotine among adolescent and adult rats to gain understanding of their potential vulnerability to the substance.

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Low Dopamine Receptor Availability May Promote Cocaine Addiction

April 2009

Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.

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Prenatal Nicotine Exposure May Damage Receptors That Influence Auditory Processing

April 2009

Reports on a series of animal experiments indicating that nicotine exposure during prenatal fetal development damages a set of receptors in the brain's auditory processing center.

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