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Chromosome 17 Harbors Opioid Dependence Genes

March 2008

Describes the work of researchers who have found a statistical link between one region on chromosome 17 and an increased risk of opioid dependence.

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Teen Substance Abuse Continues to Decline

March 2008

Reports on the prevalence of substance abuse among youth based on 2007 data from a national survey of behaviors, attitudes, and values.

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Not All Mesolimbic Dopamine Neurons Are Alike

March 2008

Reports on research showing that the neurons that deliver dopamine to two regions of the brain's mesolimbic reward system respond differently to opioids, an important finding for drug treatment research.

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Alcohol Abuse Makes Prescription Drug Abuse More Likely

March 2008

Reports on results from a study showing that men and women with alcohol use disorders are more likely to report nonmedical use of prescription drugs than people who don't drink at all.

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Cocaine Can Mobilize Stored Dopamine

March 2008

Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.

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Chronic Cocaine Abusers Have Occult Insomnia in Early Abstinence

March 2008
Reports on research of chronic cocaine abusers who may feel they are sleeping better during early abstinence revealed that the opposite may be true.

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NIDA's Newest Division Mines Clinical Applications From Basic Research

October 2007

Describes the role of the Division of Clinical Neuroscience and Behavioral Research in NIDA’s drug abuse and addiction research plan.

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Exposure to Morphine During Early Adolescence Sensitizes Rats as Adults

October 2007

Presents highlights of a study indicating that exposure to morphine during adolescence may increase sensitivity to the drug during adulthood.

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Gene Experiment Confirms a Suspected Cocaine Action

October 2007

Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.

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