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NIDA Notes Articles

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Substance Abuse Among Older Adults

December 2011

Understanding and responding to drug abuse among America’s aging population becomes more urgent as a growing percentage of baby boomers enter the over-50 age bracket.

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Individual Differences in Decisionmaking Style May Predict Teen Problems

December 2011

Reports on the relative influence of genes versus environment on adolescents’ choices that involve delayed gratification.

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Molecular Alterations of DNA Contribute to Persistence of Memory

November 2011
In a new series of studies tracing the molecular events that occur in the brain as memories are formed and preserved, researchers find that certain epigenetic changes may promote vulnerability to relapse.

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Girls More Likely Than Boys to Use Ecstasy

November 2011
Lifetime ecstasy use is more prevalent among adolescent girls than among adolescent boys, according to an analysis of 2002–2008 data from the National Survey on Drug Use and Health.

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Resting Brain Studies Shed New Light on Vulnerabilities

November 2011

Individuals with weak signaling in a nicotine-sensitive brain circuit were more vulnerable to nicotine dependence than those with stronger signaling, according to a study conducted while the subjects’ brains were in a resting state. A second resting-state study finds that the same circuit appears to mediate dependence associated with a genetic risk factor for smoking.

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New Class of Regulators for Addiction Genes

November 2011
New studies show that microRNAs, snippets of RNA implicated in a wide variety of biological processes, are involved in promoting and inhibiting cocaine addiction. The findings could pave a new path for the development of anti-addiction therapies.

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Good-Bye, Paper

November 2011

NIDA Notes becomes an All-Web publication in 2012. Issue 2 of Volume 24 will be the last print issue.

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Nanotechnology Powers Smart Skin Patch

November 2011

An in vitro test demonstrates the potential of a programmable skin patch that will enable physicians to tailor transdermal medication doses to match patients' fluctuating needs.

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NIDA's Drug Abuse Research Advances Science as a Whole

November 2011

NIDA Director Dr. Nora D. Volkow summarizes instances where discoveries with broad implications for human health arose from scientists seeking answers to addiction problems.

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Disruption of Neuron Production in Adult Rats Increases Cocaine Taking

November 2011
Drug abuse may diminish production of new neurons in the brain’s hippocampus and thereby increase vulnerability to drug addiction.

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