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NIDA Notes Articles: Prevention Research

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Alleviation of Posttraumatic Stress Disorder May Improve Addiction Treatment

April 2012

Women with posttraumatic stress disorder (PTSD) who abused drugs responded better to substance abuse treatment after their PTSD symptoms improved, according to a recent study, which also found that reductions in substance abuse did not ease PTSD severity

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Physical Activity Reduces Return to Cocaine Seeking in Animal Tests

April 2012

Two independent animal studies suggest that aerobic exercise might help cocaine abusers establish and maintain abstinence.

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Desire to Smoke Subsides, But Cigarette Cues Retain Power

April 2012

During early abstinence, smokers’ cravings triggered by cigarette cues intensified over time, providing evidence that people can experience a phenomenon previously observed in experiments with animals

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Antiretroviral Treatment Reduces Spread of HIV Among Injection Drug Users

April 2012
Expanded use of antiretroviral therapy in British Columbia reduced the spread of HIV among injection drug users and others in the province.

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Women and Sex/Gender Differences Research Program

April 2012
NIDA’s Women and Sex/Gender Differences Research Program focuses on gender-specific addiction risk factors and treatment needs.

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Vouchers Improve Mothers’ Smoking Abstinence and Newborns’ Weight

April 2012

Pregnant women who received financial incentives to refrain from smoking during late pregnancy were more successful at remaining abstinent and less likely to have babies with low birth weight, according to data from three trials.

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Well-Known Mechanism Underlies Benzodiazepines' Addictive Properties

April 2012
New research establishes that benzodiazepines cause addiction in a way similar to that of opioids, cannabinoids, and the club drug GHB. The discovery opens the door to designing new benzodiazepines that counteract anxiety but are not addictive.

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Peers Increase Teen Driving Risk via Heightened Reward Activity

March 2012
Adolescent, but not adult, drivers are more likely to take risks when peers are watching, a new study suggests.

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NIDA Announces Avant-Garde Medication Development Awards

March 2012
Dr. Thomas Kosten of Baylor College of Medicine and Dr. Peter Burkhard of the University of Connecticut are the recipients of NIDA’s 2011 Avant-Garde Awards for Innovative Medication Development Research. Dr. Kosten is developing a vaccine against methamphetamine abuse and Dr. Burkhard is developing a vaccine to counter nicotine addiction.

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In Animals, Receptor Puts Brakes on Nicotine Consumption

March 2012

New research suggests that differences in tobacco consumption reflect, in part, differences in the functional efficacy of a specific type of receptor in a pathway of the brain. In animal studies, nicotinic acetylcholine receptors with the α5 subunit played a key role in producing aversive responses to nicotine, thereby dissuading further consumption of the drug.

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