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NIDA Notes Articles

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Long-Term Cocaine Self-Administration Depresses Brain Activity

December 2008

Discusses research exploring how widespread the reduction of neural activity is in the brain with chronic exposure to cocaine.

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Brain Proteins Differ in Cocaine-Overdose Victims

December 2008

Describes research findings showing differences in protein concentrations in the brain pleasure centers of people who died from cocaine overdose as compared with those who did not abuse the drug.

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New Vaccines Are Being Developed Against Addiction and Relapse

December 2008

Highlights NIDA-funded research to develop vaccines against addiction to drugs such as cocaine, nicotine, phencyclidine (PCP), and methamphetamine.

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Henry Yamamura Obituary

December 2008

Remembers Henry I. "Hank" Yamamura, an eminent neuropharmacologist who pioneered radioligand binding assays, contributing valuable knowledge about neurotransmitter transporters and receptors.

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Methadone Reduces Rats' Cocaine Seeking

December 2008

Reports on an animal study showing that methadone, normally used as a therapy for opioid abuse, may prove to be an effective treatment for cocaine abuse.

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Reducing Postpartum Drug Use

December 2008

Highlights a computerized intervention that reduced new mothers' drug abuse in the first 4 months postpartum as reported in a clinical trial of 107 women who abused drugs.

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High-Risk Drug Offenders Do Better With Close Judicial Supervision

December 2008

Reports on research showing that increasing the mandatory drug court monitoring sessions for high-risk drug offenders can enhance program success rates.

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Nicotine Dependence is Linked With Mental Disorders in Pregnant Women

December 2008

Reports on a link between mental disorders, including mood, anxiety, or personality disorder and nicotine dependence in pregnancy women.

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Aripiprazole Prevents Rats From Resuming Cocaine Seeking

December 2008

Reports on study results indicating a medication prescribed for schizophrenia and manic phases of bipolar disorder shows promise as a cocaine addiction treatment.

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Optical Technologies Expand Vistas Into the Brain

September 2008

Describes new tools under development, including one to visualize cells deep in the brain and another one that remotely activates brain cells.

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