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NIDA Notes Articles: People with Drug Use Disorders

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Court Mandates Help Men With Antisocial Personality Disorders Stay in Treatment

April 2009
Reports on a study of men with co-occurring substance abuse and antisocial personality disorders and the potential benefit of judicially mandated addiction treatment.

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Damage to Brain Area May Immediately Halt Cigarette Addiction

April 2009
Describes a study among people who had sustained brain injuries to investigate whether certain damaged areas of the brain are associated with the ability to quit smoking.

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NIDA Centers Raise Physicians' Awareness of Drug Abuse Issues

December 2008
Highlights four Centers of Excellence for Physician Information designed to increase physicians' awareness of research on the medical consequences of drug abuse and addiction and incorporate research findings into clinical practice.

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Brain Proteins Differ in Cocaine-Overdose Victims

December 2008
Describes research findings showing differences in protein concentrations in the brain pleasure centers of people who died from cocaine overdose as compared with those who did not abuse the drug.

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New Vaccines Are Being Developed Against Addiction and Relapse

December 2008

Highlights NIDA-funded research to develop vaccines against addiction to drugs such as cocaine, nicotine, phencyclidine (PCP), and methamphetamine.

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Reducing Postpartum Drug Use

December 2008
Highlights a computerized intervention that reduced new mothers' drug abuse in the first 4 months postpartum as reported in a clinical trial of 107 women who abused drugs.

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High-Risk Drug Offenders Do Better With Close Judicial Supervision

December 2008
Reports on research showing that increasing the mandatory drug court monitoring sessions for high-risk drug offenders can enhance program success rates.

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Lofexidine May Enhance Naltrexone Efficacy

December 2008
Highlights results from a pilot study suggesting that lofexidine, an anti-hypertensive medication, can enhance success rates among patients taking maintenance naltrexone to avoid opioid relapse.

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Imaging Studies Elucidate Neurobiology of Cigarette Craving

December 2008
Reports on three separate imaging studies illuminating the neurobiology of cigarette craving.

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New Technique Links 89 Genes to Drug Dependence

September 2008
Presents research findings linking 89 genes to drug abuse and dependence, found using genome-wide association studies, a new technique for identifying genes.

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