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NIDA Notes Articles: People with Drug Use Disorders

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Abstinent Smokers' Nicotinic Receptors Take More Than a Month to Normalize

October 2009
Describes research revealing that for up to 6 weeks after smokers quit, their brain cells have more nicotine-binding receptors than nonsmokers, which may explain the struggle to quit.

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Drug Cues Outside Awareness Rapidly Trigger Brain's Emotion Centers

October 2009
Describes research showing that cocaine abusers appear to have a rapid neural response to reward cues outside of their awareness, possibly signifying vulnerability to relapse.

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Suiting Treatment to the Nature of the Disease

October 2009

Highlights NIDA-sponsored research underway to understand and respond to substance abusers’ needs at all points of care, from the initial presentation for treatment through recovery.

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Sensory Aspects of Smoking May Counter Bad Mood, Craving

October 2009
Describes study findings revealing that the act of smoking, apart from actual or expected nicotine delivery, may soothe a smoker's negative mood.

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Conferees Discuss Ways to Eliminate Disparities in Care

October 2009
Presents highlights of a meeting summit to discuss ways to eliminate disparities in care, particularly as they relate to drug abuse and HIV.

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Methamphetamine Abusers Show Increased Distractibility

April 2009
Highlights findings from a study of former methamphetamine abusers showing evidence of impairment in areas of the brain known to influence cognition, emotion, and decision making.

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NIDA's National Advisory Council Welcomes New Members

April 2009
Introduces five new members to the NIDA National Advisory Council meeting, including Drs. Xavier Castellanos, Steven Childers, Thomas Crowley, Anita Everett, and Hazel Szeto.

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Legal Pressure Increases Treatment Retention

April 2009
Presents data on the length of stay in substance abuse treatment among people who were in treatment as a result of legal pressure as compared with those in treatment voluntarily.

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Cocaine Locks Rats Into Unrewarding Behaviors

April 2009
Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.

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Court Mandates Help Men With Antisocial Personality Disorders Stay in Treatment

April 2009
Reports on a study of men with co-occurring substance abuse and antisocial personality disorders and the potential benefit of judicially mandated addiction treatment.

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